Evidence map›Paper›PMID 18684720›Full record

ReviewProceedings of the American Thoracic Society2008

Bone marrow-derived lung epithelial cells.

Diane S Krause

Abstract readReview
In one paragraph

Review in Proceedings of the American Thoracic Society, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Stem cells and cell therapies in lung biology and lung diseases.Proceedings of the American Thoracic Society · 2011
    Article
  8. Microchimerism in salivary glands after blood- and marrow-derived stem cell transplantation.Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation · 2011
    Article
  9. Circulating CD34(+) cells are elevated in neonates with respiratory distress syndrome.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2010
    Article
  10. Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Diane S KrauseYale University School of Medicine, 333 Cedar St., New Haven, CT 06510, USA. diane.krause@yale.edu

Funding

TRANSCRIPTION FACTORS/ GENETIC SEQUENCES REQUIRED FOR CD34 IN EARLY HEMATOPOIESISP01HL063357 · NHLBI · YALE UNIVERSITY · PI FORGET, BERNARD G · 1999 to 2008
$17.4M
Type II pneumocyte engraftment of bone marrow stem cellsR01HL073742 · NHLBI · YALE UNIVERSITY · PI KRAUSE, DIANE S · 2003 to 2012
$3.5M
Epithelial engraftment of bone marrow derived stem cellsR01DK061846 · NIDDK · YALE UNIVERSITY · PI KRAUSE, DIANE S · 2001 to 2008
$2.5M
NHLBI NIH HHS P01 HL63357NHLBI NIH HHS R01 HL073742NIDDK NIH HHS NIH R01 DK61846
6 · The paper itself

Abstract

Bone marrow-derived cells can take on the phenotype of epithelial cells and express epithelial-specific genes in multiple organs. Here, we focus on recent data on the appearance of marrow-derived epithelial cells in the adult lung. These findings have garnered significant skepticism because in most cases marrow-derived epithelial cells are very rare, the marrow cell of origin is not known, the techniques for detection have needed improvement, and there seem to be multiple mechanisms by which this occurs. Recent studies have focused on these concerns. Once these important concerns are addressed, further studies on the function(s) of these cells will need to be performed to determine whether this engraftment has any clinical significance-either beneficial or detrimental.

Indexed as

AdultBone Marrow CellsCell DifferentiationEpithelial CellsHumansLungRespiratory Mucosa

Identifiers

PMID18684720
PMCPMC2645262

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.