Evidence map›Paper›PMID 18684639›Full record

ArticleJournal of the American Society for Mass Spectrometry2008

Transmission mode desorption electrospray ionization.

Joseph E Chipuk, Jennifer S Brodbelt

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of the American Society for Mass Spectrometry, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Article
  2. Review
  3. Transferring Ions from Solution to the Gas Phase: The Two Basic Principles.Journal of the American Society for Mass Spectrometry · 2017
    Article
  4. Online Monitoring of Methanol Electro-Oxidation Reactions by Ambient Mass Spectrometry.Journal of the American Society for Mass Spectrometry · 2017
    Article
  5. Towards Practical Endoscopic Mass Spectrometry.Mass spectrometry (Tokyo, Japan) · 2017
    Article
  6. Article
  7. Article
  8. Multistage Reactive Transmission-Mode Desorption Electrospray Ionization Mass Spectrometry.Journal of the American Society for Mass Spectrometry · 2015
    Article
  9. Article
  10. A new splitting method for both analytical and preparative LC/MS.Journal of the American Society for Mass Spectrometry · 2014
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. What can we learn from ambient ionization techniques?Journal of the American Society for Mass Spectrometry · 2009
    Review
  19. Article
  20. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Joseph E ChipukDepartment of Chemistry and Biochemistry, University of Texas at Austin, Austin, Texas 78712, USA.
Jennifer S Brodbelt

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A new mode of operation for desorption electrospray ionization (DESI) analysis of liquids or solid residues from evaporated solvents is presented. Unlike traditional DESI, the electrospray is not deflected off of a surface but instead is transmitted through a sampling mesh at a 0 degrees angle between the electrospray tip, sample mesh, and capillary inlet of a mass spectrometer. In this configuration, deposited samples can be analyzed rapidly without rigorous optimization of spray distances or angles and without the preparation time associated with solvent evaporation. The new transmission mode desorption electrospray ionization (TM-DESI) technique is not applicable to bulk materials, but instead is a method designed to simplify the sample preparation process for liquid samples and sample extracts. The technique can reduce analysis time to seconds while consuming only microliters of sample. The results presented summarize the optimization of the technique, highlight key figures of merit for several model compounds, and illustrate potential applications to high throughput screening of liquid mixtures in both extraction solvents and biological matrices.

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.