ArticleBiology direct2008
A highly conserved family of inactivated archaeal B family DNA polymerases.
Article in Biology direct, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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Who cites it
26 citing papers in PubMed.
- Common themes in architecture and interactions of prokaryotic PolB2 and Pol V mutasomes inferred fromComputational and structural biotechnology journal · 2025Article
- A Well-Conserved Archaeal B-Family Polymerase Functions as an Extender in Translesion Synthesis.mBio · 2022Article
- Review
- Diversity and evolution of B-family DNA polymerases.Nucleic acids research · 2020Review
- The replication machinery of LUCA: common origin of DNA replication and transcription.BMC biology · 2020Article
- A Unique B-Family DNA Polymerase Facilitating Error-Prone DNA Damage Tolerance in Crenarchaeota.Frontiers in microbiology · 2020Article
- An Orc1/Cdc6 ortholog functions as a key regulator in the DNA damage response in Archaea.Nucleic acids research · 2018Article
- Two Family B DNA Polymerases FromFrontiers in molecular biosciences · 2018Article
- Calcium-driven DNA synthesis by a high-fidelity DNA polymerase.Nucleic acids research · 2017Article
- Genomic survey and expression analysis of DNA repair genes in the genus Leptospira.Molecular genetics and genomics : MGG · 2016Article
- Fusion of a superfamily 1 helicase and an inactivated DNA polymerase is a signature of common evolutionary history of Polintons, polinton-like viruses, Tlr1 transposons and transpovirons.Virus evolution · 2016Article
- Comparison of the kinetic parameters of the truncated catalytic subunit and holoenzyme of human DNA polymerase ɛ.DNA repair · 2015Article
- Chordopoxvirus protein F12 implicated in enveloped virion morphogenesis is an inactivated DNA polymerase.Biology direct · 2014Article
- Sulfolobus replication factor C stimulates the activity of DNA polymerase B1.Journal of bacteriology · 2014Article
- Evolution of replicative DNA polymerases in archaea and their contributions to the eukaryotic replication machinery.Frontiers in microbiology · 2014Review
- Diversity of the DNA replication system in the Archaea domain.Archaea (Vancouver, B.C.) · 2014Review
- Archaeology of eukaryotic DNA replication.Cold Spring Harbor perspectives in biology · 2013Review
- Sulfolobus chromatin proteins modulate strand displacement by DNA polymerase B1.Nucleic acids research · 2013Article
- Coordination of multiple enzyme activities by a single PCNA in archaeal Okazaki fragment maturation.The EMBO journal · 2012Article
- Kinetics and fidelity of polymerization by DNA polymerase III from Sulfolobus solfataricus.Biochemistry · 2012Article
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Authors and funding
4 authors.
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Abstract
A widespread and highly conserved family of apparently inactivated derivatives of archaeal B-family DNA polymerases is described. Phylogenetic analysis shows that the inactivated forms comprise a distinct clade among archaeal B-family polymerases and that, within this clade, Euryarchaea and Crenarchaea are clearly separated from each other and from a small group of bacterial homologs. These findings are compatible with an ancient duplication of the DNA polymerase gene followed by inactivation and parallel loss in some of the lineages although contribution of horizontal gene transfer cannot be ruled out. The inactivated derivative of the archaeal DNA polymerase could form a complex with the active paralog and play a structural role in DNA replication.
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