ArticleGraefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie2008
Intravitreal bevacizumab for refractory choroidal neovascularization (CNV) secondary to uveitis.
Article in Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02015351 (Intravitreal Bevacizumab for the Treatment of Choroidal Neovascularization in Vogt-Koyanagi-Harada Disease - A Prospective Study), which is not on this map. Cited by 16 papers.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Intravitreal Bevacizumab for the Treatment of Choroidal Neovascularization in Vogt-Koyanagi-Harada Disease - A Prospective Study
Who cites it
16 citing papers in PubMed, 45 citations in OpenAlex.
- Anti-vascular endothelial growth factor therapy in uveitis: Bridging inflammation and vascular pathology.Indian journal of ophthalmology · 2026Review
- Inflammatory Choroidal Neovascular Membranes in Patients With Noninfectious Uveitis: The Place of Intravitreal Anti-VEGF Therapy.Medical hypothesis, discovery & innovation ophthalmology journal · 2020Review
- Choroidal neovascularization secondary to tuberculosis: Presentation and management.American journal of ophthalmology case reports · 2017Article
- Aflibercept for inflammatory choroidal neovascularization with persistent fluid on intravitreal ranibizumab therapy.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2014Article
- Management of uveitis-related choroidal neovascularization: from the pathogenesis to the therapy.Journal of ophthalmology · 2014Review
- Treatment of experimental autoimmune uveoretinitis with peroxisome proliferator-activated receptor α agonist fenofibrate.Molecular vision · 2014Article
- Risk of choroidal neovascularization among the uveitides.American journal of ophthalmology · 2013Article
- Five-year visual results of intravitreal bevacizumab in refractory inflammatory ocular neovascularization.Clinical ophthalmology (Auckland, N.Z.) · 2012Article
- Myopia and inflammation.Journal of ophthalmic & vision research · 2011Article
- The use of intravitreal ranibizumab for choroidal neovascularization associated with vogt-koyanagi-harada syndrome.Case reports in medicine · 2011Article
- Association of systemic steroids and mycophenolate mofetil as rescue therapy for uveitic choroidal neovascularization unresponsive to the traditional immunosuppressants: interventional case series.International ophthalmology · 2010Article
- Verteporfin PDT for non-standard indications--a review of current literature.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2010Review
- Inflammatory choroidal neovascularization.Middle East African journal of ophthalmology · 2009Article
- Results of Intravitreal Anti-Vascular Endothelial Growth Factor Therapy in Inflammatory Choroidal Neovascularization.Journal of current ophthalmologyArticle
- Autofluorescence findings and role of anti-vascular endothelial growth factor in inflammatory choroidal neovascular membrane.Indian journal of ophthalmologyArticle
- Serpiginous choroiditis and infectious multifocal serpiginoid choroiditis.Survey of ophthalmologyReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo assess the short-term efficacy and safety of intravitreal bevacizumab injections (IVB) for refractory choroidal neovascularization (CNV) secondary to uveitis.
methodsTen patients affected by choroidal neovascularization secondary to uveitis unresponsive to immunosuppression associated or not with photodynamic therapy (PDT) were consecutively included. All patients underwent a complete ophthalmic examination including best-corrected visual acuity (BCVA), fluorescein (FA) and indocyanine green angiographies (ICG), optical coherence tomography (OCT) at baseline, and after IVB injection (1.25 mg/0.05 ml).
resultsCNV was subfoveal in eight cases and juxtafoveal in two cases. Mean follow-up was 7.5 months. After treatment, the logMAR BCVA improved from 0.62 +/- 0.4 (Snellen equivalent of 20/55) to 0.45 +/- 0.35 (Snellen equivalent of 20/40) at 1 month (p = 0.01), then remained stable during the follow-up. Mean central macular thickness (CMT) was reduced from 326 +/- 95 microm before treatment to 267 +/- 28 microm (p = 0.03) at last visit. Mean number of IVB was 2.5. Leakage from inflammatory CNV was stopped in three eyes and decreased in seven eyes. No systemic or ocular adverse events were recorded.
conclusionsIntravitreal bevacizumab improves BCVA and reduces central macular thickness in eyes with inflammatory CNV refractory to immunosuppression associated or not with PDT. Further study is necessary to assess the efficacy and safety in the long term.
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