Evidence map›Paper›PMID 18682917›Full record

ArticleIntensive care medicine2008

FDG-PET in patients at risk for acute respiratory distress syndrome: a preliminary report.

R S Rodrigues, P R Miller, F A Bozza, E Marchiori, G A Zimmerman, J M Hoffman, K A Morton

Abstract readEvaluation Study
PubMed Publisher
In one paragraph

Article in Intensive care medicine, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
6.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 67 citations in OpenAlex.

  1. Trial
  2. Article
  3. Review
  4. Post-Traumatic Pulmonary Hematoma Presenting as Multiple Ring-shaped Spherical Nodules.American journal of respiratory and critical care medicine · 2023
    Article
  5. Article
  6. High-Temporal-Resolution Lung Kinetic Modeling Using Total-Body Dynamic PET with Time-Delay and Dispersion Corrections.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2023
    Article
  7. Article
  8. Article
  9. Positron emission tomography in the COVID-19 pandemic era.European journal of nuclear medicine and molecular imaging · 2021
    Review
  10. Review
  11. Review
  12. Article
  13. Article
  14. Article
  15. Review
  16. Nuclear medicine and biology · 2017
    Article
  17. Imaging Pulmonary Inflammation.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2016
    Review
  18. Article
  19. PET/CT in nononcological lung diseases: current applications and future perspectives.European respiratory review : an official journal of the European Respiratory Society · 2016
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 2 countries.

R S RodriguesDepartment of Radiology, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.
P R Miller
F A Bozza
E Marchiori
G A Zimmerman
J M Hoffman
K A Morton
University of Utah · USFundação Oswaldo Cruz · BRUniversidade Federal do Rio de Janeiro · BRUniversidade Federal Fluminense · BRWake Forest University · US

Funding

MOLECULAR INTERACTIONS OF MYELOID CELLS WITH ENDOTHELIUMR01HL044525 · NHLBI · UNIVERSITY OF UTAH · PI ZIMMERMAN, GUY A. · 1990 to 2003
$1.2M
NHLBI NIH HHS R01 HL044525
6 · The paper itself

Abstract

objectiveTo compare the pattern of lung uptake of 18F-fluorodeoxyglucose (FDG) by positron emission tomography (PET) imaging in patients with lung contusion that developed or did not progress to acute respiratory distress syndrome (ARDS).

designProspective, observational study.

settingTrauma Center (academic urban hospital). PATIENTS AND

interventionsEight patients with blunt thoracic trauma and pulmonary contusion, confirmed by computed tomography (CT) on admission, underwent repeat CT and FDG-PET (on the same day) 24-72 h after admission.

resultsNo subjects met the criteria for ARDS at the time of the PET and second CT. Four subjects subsequently developed ARDS 1-3 days after the PET scan; the other four did not develop the syndrome. Three of the four subjects who subsequently developed ARDS showed diffuse FDG uptake throughout the entire lungs, while those who did not develop ARDS showed significant FDG uptake only in areas of focal lung opacity (non or poorly aerated lung units) on CT. FDG uptake in normally aerated lung regions was higher for those who subsequently developed ARDS than those who did not, approaching statistical significance. The normally aerated tissue:liver ratio was significantly higher in subjects who developed ARDS than in those who did not (P = 0.029).

conclusionIn this small series of patients with thoracic trauma, diffuse lung uptake of FDG was detected by PET imaging 1-3 days prior to clinically determined ARDS.

Indexed as

Positron-Emission TomographyAcute Lung InjuryAdolescentAdultAgedCohort StudiesEarly DiagnosisFemaleFluorodeoxyglucose F18HumansMaleMiddle AgedPilot ProjectsPredictive Value of TestsRadiopharmaceuticalsRespiratory Distress SyndromeFluorodeoxyglucose F18Radiopharmaceuticals

Identifiers

PMID18682917
OpenAlexW1995258884

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.