ArticleClinical autonomic research : official journal of the Clinical Autonomic Research Society2008
Optimizing squatting as a physical maneuver to prevent vasovagal syncope.
Article in Clinical autonomic research : official journal of the Clinical Autonomic Research Society, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
7 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.
- Physical manoeuvers as a preventive intervention to manage vasovagal syncope: A systematic review.PloS one · 2019Pooled it
- Physical training as non-pharmacological treatment of neurocardiogenic syncope.Arquivos brasileiros de cardiologia · 2014Trial
- Exaggerated postural sway improves orthostatic cardiovascular and cerebrovascular control.Frontiers in cardiovascular medicine · 2023Article
- Counter pressure maneuvers for syncope prevention: A semi-systematic review and meta-analysis.Frontiers in cardiovascular medicine · 2022Review
- Cardiovascular responses to leg muscle loading during head-down tilt at rest and after dynamic exercises.Scientific reports · 2019Article
- Initial orthostatic hypotension in teenagers and young adults.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2016Article
- Tilt-induced vasovagal syncope and psychogenic pseudosyncope: Overlapping clinical entities.Neurology · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesSquatting is a potent physical maneuver to prevent syncope; however, a major drawback is that standing up from squatting is a large hemodynamic stressor that often causes new presyncopal symptoms. We tested the hypothesis that lower body skeletal muscle tensing (LBMT) attenuates the decrease of mean arterial blood pressure (MAP) upon standing from squatting when used as a maneuver to prevent vasovagal syncope. METHODS AND
resultsIn 18 patients (10 females and 8 males, median age 37.5 years) we followed continuous MAP, cardiac output (CO, by Modelflow) and total peripheral resistance (TPR) during tilt test-provoked pre-syncopal episodes. After standing up from squatting MAP decreased to a nadir of 64 +/- 4 mmHg (mean +/- SE), related to a reduction in CO 73 +/- 5% of supine values. Standing up with LBMT limited the reduction in CO (85 +/- 6 %, P < 0.05) and MAP nadir (to 76 +/- 3 mmHg; P < 0.05 compared to without LBMT) with fewer or no presyncopal symptoms. Standing up from squatting with and without LBMT did not affect TPR (99 +/- 5% vs. 101 +/- 7%).
interpretationLBMT is proposed as an effective follow-up maneuver to squatting when applied to prevent syncope.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.