ReviewCurrent allergy and asthma reports2008
Innate immune mechanism in allergic asthma.
Review in Current allergy and asthma reports, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed.
- Safranal restores RUNX3-mediated immunoregulation by inhibiting the NLRP3 inflammasome in allergic asthma.Naunyn-Schmiedeberg's archives of pharmacology · 2025Article
- Link between gut microbiota dysbiosis and childhood asthma: Insights from a systematic review.The journal of allergy and clinical immunology. Global · 2024Review
- Pulmonary neuroendocrine cells: physiology, tissue homeostasis and disease.Disease models & mechanisms · 2020Review
- Short ragweed pollen promotes M2 macrophage polarization via TSLP/TSLPR/OX40L signaling in allergic inflammation.Mucosal immunology · 2019Article
- The Potential for Emerging Microbiome-Mediated Therapeutics in Asthma.Current allergy and asthma reports · 2017Review
- Article
- Properdin Contributes to Allergic Airway Inflammation through Local C3a Generation.Journal of immunology (Baltimore, Md. : 1950) · 2015Article
- Inhaled environmental allergens and toxicants as determinants of the asthma phenotype.Advances in experimental medicine and biology · 2014Review
- Lung dendritic cell developmental programming, environmental stimuli, and asthma in early periods of life.Journal of allergy · 2012Article
- Epidemiology of stress and asthma: from constricting communities and fragile families to epigenetics.Immunology and allergy clinics of North America · 2011Review
- Chronic inflammation and asthma.Mutation research · 2010Review
- Prenatal maternal stress and cord blood innate and adaptive cytokine responses in an inner-city cohort.American journal of respiratory and critical care medicine · 2010Article
- Perinatal stress and early life programming of lung structure and function.Biological psychology · 2010Review
- The role of Epac proteins, novel cAMP mediators, in the regulation of immune, lung and neuronal function.British journal of pharmacology · 2010Review
- T lymphocyte apoptosis in asthma.European journal of medical research · 2009Review
- A low dose of Mycoplasma pneumoniae infection enhances an established allergic inflammation in mice: the role of the prostaglandin E2 pathway.Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology · 2009Article
- Moving towards making social toxins mainstream in children's environmental health.Current opinion in pediatrics · 2009Review
- The adaptor protein CIKS/Act1 is essential for IL-25-mediated allergic airway inflammation.Journal of immunology (Baltimore, Md. : 1950) · 2009Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Allergic asthma is a chronic inflammatory disorder of the airways characterized by eosinophilic inflammation, airway hyperresponsiveness, and mucus hypersecretion. Adaptive, antigen-dependent immunity is critical for asthma pathogenesis. Allergic asthma may involve adaptive and innate, antigen-independent immune responses. This review discusses the current evidence that associates innate immunity with allergic asthma pathogenesis. In particular, we focus on the role of innate immune cells (eg, bronchial epithelial cells, alveolar macrophages, and dendritic cells) and molecules (Toll-like and nucleotide-binding oligomerization domain-like receptors) in modifying allergic immune responses.
Indexed as
Identifiers
18682113What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.