ReviewAnnual review of genetics2008
Design features of a mitotic spindle: balancing tension and compression at a single microtubule kinetochore interface in budding yeast.
Review in Annual review of genetics, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed.
- Humanization reveals pervasive incompatibility of yeast and human kinetochore components.G3 (Bethesda, Md.) · 2023Article
- Force by minus-end motors Dhc1 and Klp2 collapses the S. pombe spindle after laser ablation.Biophysical journal · 2022Article
- Centromere Tension Measurement in Budding Yeast Mitosis.Methods in molecular biology (Clifton, N.J.) · 2022Article
- Towards a synthetic cell cycle.Nature communications · 2021Review
- Astral microtubule forces alter nuclear organization and inhibit DNA repair in budding yeast.Molecular biology of the cell · 2019Article
- The yeast kinesin-5 Cin8 interacts with the microtubule in a noncanonical manner.The Journal of biological chemistry · 2017Article
- Anaphase B.Biology · 2016Review
- NuSAP modulates the dynamics of kinetochore microtubules by attenuating MCAK depolymerisation activity.Scientific reports · 2016Article
- Buckling behavior of individual and bundled microtubules.Biophysical journal · 2015Article
- Article
- A mathematical model of force generation by flexible kinetochore-microtubule attachments.Biophysical journal · 2014Article
- Distinct roles for antiparallel microtubule pairing and overlap during early spindle assembly.Molecular biology of the cell · 2013Article
- Astral microtubule asymmetry provides directional cues for spindle positioning in budding yeast.Experimental cell research · 2012Review
- Actin depolymerization drives actomyosin ring contraction during budding yeast cytokinesis.Developmental cell · 2012Article
- Mitotic spindle form and function.Genetics · 2012Article
- Bub1 kinase and Sgo1 modulate pericentric chromatin in response to altered microtubule dynamics.Current biology : CB · 2012Article
- Functional centromeres determine the activation time of pericentric origins of DNA replication in Saccharomyces cerevisiae.PLoS genetics · 2012Article
- Article
- A role for histone H4K16 hypoacetylation in Saccharomyces cerevisiae kinetochore function.Genetics · 2011Article
- Association of a centromere specific nucleosome with the yeast plasmid partitioning locus: Implications beyond plasmid partitioning.Mobile genetic elements · 2011Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
Accurate segregation of duplicated chromosomes ensures that daughter cells get one and only one copy of each chromosome. Errors in chromosome segregation result in aneuploidy and have severe consequences on human health. Incorrect chromosome number and chromosomal instability are hallmarks of tumor cells. Hence, segregation errors are thought to be a major cause of tumorigenesis. A study of the physical mechanical basis of chromosome segregation is essential to understand the processes that can lead to errors. Tremendous progress has been made in recent years in identifying the proteins necessary for chromosome movement and segregation, but the mechanism and structure of critical force generating components and the molecular basis of centromere stiffness remain poorly understood.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.