Evidence map›Paper›PMID 18680221›Full record

ReviewWorld journal of gastroenterology2008

Thrombosis and inflammatory bowel disease-the role of genetic risk factors.

Georgia Tsiolakidou, Ioannis-E Koutroubakis

Open access · hybridAbstract readEditorialReview
In one paragraph

Review in World journal of gastroenterology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it, 51 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Article
  5. Review
  6. Inflammatory bowel disease and thromboembolic events: a c'lot to learn.Therapeutic advances in gastroenterology · 2022
    Article
  7. Review
  8. Review
  9. Role of Vitamin K in Intestinal Health.Frontiers in immunology · 2021
    Review
  10. Review
  11. Review
  12. Structural brain lesions in inflammatory bowel disease.World journal of gastrointestinal pathophysiology · 2015
    Review
  13. Article
  14. Inflammatory bowel disease and thromboembolism.World journal of gastroenterology · 2014
    Review
  15. Review
  16. Review
  17. Review
  18. Extraintestinal manifestations and complications in IBD.Nature reviews. Gastroenterology & hepatology · 2013
    Review
  19. Inflammatory bowel disease and thrombosis.Turkish journal of haematology : official journal of Turkish Society of Haematology · 2012
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Georgia Tsiolakidou
Ioannis-E Koutroubakis
University Hospital of Heraklion · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Thromboembolism is a significant cause of morbidity and mortality in patients with inflammatory bowel disease (IBD). Recent data suggest thromboembolism as a disease-specific extraintestinal manifestation of IBD, which is developed as the result of multiple interactions between acquired and genetic risk factors. There is evidence indicating an imbalance of procoagulant, anticoagulant and fibrinolitic factors predisposing in thrombosis in patients with IBD. The genetic factors that have been suggested to interfere in the thrombotic manifestations of IBD include factor V Leiden, factor II (prothrombin, G20210A), methylenetetrahydrofolate reductase gene mutation (MTHFR, 6777T), plasminogen activator inhibitor type 1 (PAI-1) gene mutation and factor XIII (val34leu). In this article we review the current data and future prospects on the role of genetic risk factors in the development of thromboembolism in IBD.

Indexed as

Factor VGenetic Predisposition to DiseaseHumansInflammatory Bowel DiseasesMutationProthrombinRisk FactorsThrombosisFactor Vfactor V LeidenProthrombin

Identifiers

PMID18680221
PMCPMC2731268
OpenAlexW2155826304

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.