Evidence map›Paper›PMID 18678958›Full record

Trial reportThe Journal of orthopaedic and sports physical therapy2008

The role of pulse duration and stimulation duration in maximizing the normalized torque during neuromuscular electrical stimulation.

Ashraf S Gorgey, Gary A Dudley

Registry-linked trialAbstract readRandomized Controlled Trial
In one paragraph

Trial report in The Journal of orthopaedic and sports physical therapy, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03905772 (Neuromuscular Adaptations After Training With Neuromuscular Electrical Stimulation Applied Over Nerve Trunk Compared With a Muscle Belly of Triceps Surae), which is not on this map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03905772 nasuspendednot on this mapstarted 2019, after this paper: background citation

Neuromuscular Adaptations After Training With Neuromuscular Electrical Stimulation Applied Over Nerve Trunk Compared With a Muscle Belly of Triceps Surae: Randomized Controlled Trial

TypeinterventionalSponsorUniversity of BrasiliaRan2019 to 2023Enrolled60ConditionsElectrical StimulationArmsVoluntary exercise, Wide pulse responder group, Wide pulse non responder group, Pulsed current group
3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it.

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  10. Transcutaneous Spinal Stimulation From Adults to Children: A Review.Topics in spinal cord injury rehabilitation · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Ashraf S GorgeyDepartment of Physical Therapy, Indiana University, Indianapolis, IN 46202-5119, USA. agorgey@gmail.com
Gary A Dudley

Funding

Skeletal muscle plasticity, fitness and health after SCIR01HD039676 · NICHD · UNIVERSITY OF GEORGIA (UGA) · PI MCCULLY, KEVIN K. · 2001 to 2013
$3.5M
NICHD NIH HHS HD39676S2NICHD NIH HHS HD39679NICHD NIH HHS R01 HD039676
6 · The paper itself

Abstract

STUDY

designControlled laboratory study

objectivesTo determine the effects of pulse duration and stimulation duration on the evoked torque after controlling for the activated area by using magnetic resonance imaging (MRI).

backgroundNeuromuscular electrical stimulation (NMES) is commonly used in the clinic without considering the physiological implications of its parameters. METHODS AND MEASURES: Seven able-bodied, college students (mean +/- SD age, 28 +/- 4 years) participated in this study. Two NMES protocols were applied to the knee extensor muscle group in a random order. Protocol A applied 100-Hz, 450-microsecond pulses for 5 minutes in a 3-seconds-on 3-seconds-off duty cycle. Protocol B applied 60-Hz, 250-microsecond pulses for 5 minutes in a 10-seconds-on 20-seconds-off duty cycle. The amplitude of the current was similar in both protocols. Torque, torque time integral, and normalized torque for the knee extensors were measured for both protocols. MRI scans were taken prior to, and immediately after, each protocol to measure the cross-sectional area of the stimulated muscle.

resultsThe skeletal muscle cross-sectional areas activated after both protocols were similar. The longer pulse duration in protocol A elicited 22% greater torque output than that of protocol B (P<.05). After considering the activated area in both protocols, the normalized torque with protocol A was 38% greater than that with protocol B (P<.05). Torque time integral was 21% greater with protocol A (P = .029). Protocol B failed to maintain torque at the start and the end of the 10-second activation.

conclusionsLonger pulse duration, but not stimulation duration, resulted in a greater evoked and normalized torque compared to the shorter pulse duration, even after controlling for the activated muscular cross-sectional areas with both protocols. LEVEL OF EVIDENCE: Therapy, level 5.

Indexed as

AdultElectric Stimulation TherapyFemaleHumansKnee JointMagnetic Resonance ImagingMaleMuscle Strength DynamometerMuscle WeaknessMuscular AtrophyTorqueYoung Adult

Identifiers

PMID18678958
PMCPMC2554670

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.