ArticleProceedings of the National Academy of Sciences of the United States of America2008
A triallelic system of S5 is a major regulator of the reproductive barrier and compatibility of indica-japonica hybrids in rice.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 128 papers, 1 of them a synthesis that pooled it.
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Who cites it
128 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Metabolite-Based Genome-Wide Association Studies of Large-Scale Metabolome Analysis to Illustrate Alterations in the Metabolite Landscape of Plants upon Responses to Stresses.Methods in molecular biology (Clifton, N.J.) · 2023Guideline
- Cross incompatibility restricting genome exchange and diversification of primary gene pool in plants: challenges and opportunities.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2026Review
- Gametocidal genes: biological mechanisms owing to hybrid dysgenesis in crop breeding, challenges and innovation.Annals of botany · 2026Review
- Structural Variations Contribute to Subspeciation and Yield Heterosis in Rice.Plant biotechnology journal · 2025Article
- Evolutionary histories of functional mutations during the domestication and spread ofProceedings of the National Academy of Sciences of the United States of America · 2025Article
- Identification of a Novel Rice Chromosomal Translocation Line that Could Cause the Heterozygote Semi-Sterility and be Overcome by Genomic Duplication.Rice (New York, N.Y.) · 2025Article
- Molecular-Marker-Based Design for Breeding Indica-Japonica Hybrid Rice with Bacterial Blight Resistance.Genes · 2025Article
- Molecular and physiological basis of heterosis in hybrid rice performance.Molecular breeding : new strategies in plant improvement · 2025Review
- Identification and Genetic Analysis of Collinearity Loci for Interspecific Hybrid Sterility in Genus Oryza.Rice (New York, N.Y.) · 2025Article
- Molecular mapping of a novel locus S68 for intrasubspecific hybrid sterility in indica-indica hybrid.Scientific reports · 2025Article
- Interspecific Hybridization Enhanced Tolerance to Salinity and Cadmium Stress Through Modifying Biochemical, Physiological, and Resistance Gene Levels, Especially in Polyploid Rice: A Sustainable Way for Stress-Resilient Rice.Rice (New York, N.Y.) · 2025Article
- Identification of a novel hybrid sterility locus S67 between temperate japonica subgroup and basmati subgroup in Oryza sativa L.Scientific reports · 2024Article
- THB1, a putative transmembrane protein that causes hybrid breakdown in rice.Breeding science · 2024Article
- Cleave and Rescue gamete killers create conditions for gene drive in plants.Nature plants · 2024Article
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- Cleave and Rescue gamete killers create conditions for gene drive in plants.bioRxiv : the preprint server for biology · 2024Article
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- Characterization and fine-mapping of a new Asian rice selfish genetic locus S58 in Asian-African rice hybrids.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2023Article
- Incompatibility and Interchangeability in Molecular Evolution.Genome biology and evolution · 2023Review
- S. pombe wtf drivers use dual transcriptional regulation and selective protein exclusion from spores to cause meiotic drive.PLoS genetics · 2022Article
68 more citing papers are in PubMed but not listed here.
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20 authors.
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Abstract
Hybrid sterility is a major form of postzygotic reproductive isolation. Although reproductive isolation has been a key issue in evolutionary biology for many decades in a wide range of organisms, only very recently a few genes for reproductive isolation were identified. The Asian cultivated rice (Oryza sativa L.) is divided into two subspecies, indica and japonica. Hybrids between indica and japonica varieties are usually highly sterile. A special group of rice germplasm, referred to as wide-compatibility varieties, is able to produce highly fertile hybrids when crossed to both indica and japonica. In this study, we cloned S5, a major locus for indica-japonica hybrid sterility and wide compatibility, using a map-based cloning approach. We show that S5 encodes an aspartic protease conditioning embryo-sac fertility. The indica (S5-i) and japonica (S5-j) alleles differ by two nucleotides. The wide compatibility gene (S5-n) has a large deletion in the N terminus of the predicted S5 protein, causing subcellular mislocalization of the protein, and thus is presumably nonfunctional. This triallelic system has a profound implication in the evolution and artificial breeding of cultivated rice. Genetic differentiation between indica and japonica would have been enforced because of the reproductive barrier caused by S5-i and S5-j, and species coherence would have been maintained by gene flow enabled by the wide compatibility gene.
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