Evidence map›Paper›PMID 18678889›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2008

Y-chromosomal evidence of a pastoralist migration through Tanzania to southern Africa.

Brenna M Henn, Christopher Gignoux, Alice A Lin, Peter J Oefner, Peidong Shen, Rosaria Scozzari, Fulvio Cruciani, Sarah A Tishkoff, Joanna L Mountain, Peter A Underhill

Abstract readComparative StudyHistorical Article
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  8. Placing Ancient DNA Sequences into Reference Phylogenies.Molecular biology and evolution · 2022
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  17. Rapid evolution of a skin-lightening allele in southern African KhoeSan.Proceedings of the National Academy of Sciences of the United States of America · 2018
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Brenna M HennDepartment of Anthropology, Stanford University, Stanford, CA 94035-2117, USA. bmhenn@stanford.edu
Christopher Gignoux
Alice A Lin
Peter J Oefner
Peidong Shen
Rosaria Scozzari
Fulvio Cruciani
Sarah A Tishkoff
Joanna L Mountain
Peter A Underhill

Funding

VARIATIONS OF HUMAN DNA SEQUENCESP01GM028428 · NIGMS · STANFORD UNIVERSITY · PI CAVALLI-SFORZA, LUIGI L · 1985 to 2004
$6.8M
NIGMS NIH HHS GM28428NIGMS NIH HHS P01 GM028428
6 · The paper itself

Abstract

Although geneticists have extensively debated the mode by which agriculture diffused from the Near East to Europe, they have not directly examined similar agropastoral diffusions in Africa. It is unclear, for example, whether early instances of sheep, cows, pottery, and other traits of the pastoralist package were transmitted to southern Africa by demic or cultural diffusion. Here, we report a newly discovered Y-chromosome-specific polymorphism that defines haplogroup E3b1f-M293. This polymorphism reveals the monophyletic relationship of the majority of haplotypes of a previously paraphyletic clade, E3b1-M35*, that is widespread in Africa and southern Europe. To elucidate the history of the E3b1f haplogroup, we analyzed this haplogroup in 13 populations from southern and eastern Africa. The geographic distribution of the E3b1f haplogroup, in association with the microsatellite diversity estimates for populations, is consistent with an expansion through Tanzania to southern-central Africa. The data suggest this dispersal was independent of the migration of Bantu-speaking peoples along a similar route. Instead, the phylogeography and microsatellite diversity of the E3b1f lineage correlate with the arrival of the pastoralist economy in southern Africa. Our Y-chromosomal evidence supports a demic diffusion model of pastoralism from eastern to southern Africa approximately 2,000 years ago.

Indexed as

DemographyGenetics, PopulationAgricultureChromatography, High Pressure LiquidChromosomes, Human, YEmigration and ImmigrationGenotypeHaplotypesHistory, AncientHumansMaleMicrosatellite RepeatsModels, GeneticPolymorphism, Single NucleotideTanzania

Identifiers

PMID18678889
PMCPMC2504844

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.