ArticleRadiation medicine2008
Cytogenetic biomonitoring of oral mucosa cells from adults exposed to dental X-rays.
Article in Radiation medicine, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it, 42 citations in OpenAlex.
- Can exposure to panoramic radiographs induce genotoxic effects on the oral epithelium? A systematic review with meta-analysis.Dento maxillo facial radiology · 2022Pooled it
- Radiobiological risks following dentomaxillofacial imaging: should we be concerned?Dento maxillo facial radiology · 2021Review
- Buccal mucosa cell damage in individuals following dental X-ray examinations.Scientific reports · 2018Article
- Evidence of genotoxicity and cytotoxicity of X-rays in the oral mucosa epithelium of adults subjected to cone beam CT.Dento maxillo facial radiology · 2018Article
- Evaluation of secondary alveolar bone grafting outcomes performed after canine eruption in complete unilateral cleft lip and palate.Clinical oral investigations · 2017Article
- Effects of ionising radiation on micronucleus formation and chromosomal aberrations in Chinese radiation workers.Radiation protection dosimetry · 2016Article
- Cytogenetic biomonitoring of oral mucosa cells of crack cocaine users.Environmental science and pollution research international · 2014Article
- Evaluation of genotoxicity in patients subjected to panoramic radiography by micronucleus assay on epithelial cells of the oral mucosa.Journal of dentistry (Tehran, Iran) · 2014Article
- Mutagenicity and cytotoxicity in patients submitted to ionizing radiation.The Angle orthodontist · 2013Article
- Cytogenetic biomonitoring in children submitting to a complete set of radiographs for orthodontic planning.The Angle orthodontist · 2012Article
- Cytogenetic biomonitoring in oral mucosa cells following dental X-ray.Dento maxillo facial radiology · 2012Review
- Biomonitoring of oral epithelial cells in smokers and non-smokers submitted to panoramic X-ray: comparison between buccal mucosa and lateral border of the tongue.Clinical oral investigations · 2010Article
- Elevated blood lead levels and cytogenetic markers in buccal epithelial cells of painters in India: genotoxicity in painters exposed to lead containing paints.Environmental science and pollution research international · 2010Article
- Biomonitoring of DNA damage and cytotoxicity in individuals exposed to cone beam computed tomography.Dento maxillo facial radiology · 2010Article
- GENOTOXICITY AND CYTOTOXICITY OF X-RAYS IN CHILDREN EXPOSED TO PANORAMIC RADIOGRAPHY.Revista paulista de pediatria : orgao oficial da Sociedade de Pediatria de Sao PauloArticle
Corrections and comments
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Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeAlthough it has been clearly demonstrated that X-rays play a key role in diagnosing medical and dental problems, this type of ionizing radiation is also able to induce noxious activities, such as genetic damage. The aim of the present study was to evaluate DNA damage (micronucleus) and cellular death in exfoliated buccal mucosa cells from healthy individuals (smokers and nonsmokers) following dental X-ray exposure. MATERIAL AND
methodsA total of 39 healthy people who had submitted to panoramic dental radiography were included in the study: 9 smokers and 30 nonsmokers.
resultsThe results indicated no significant statistically differences (P>0.05) in micronucleated oral mucosa cells before and after dental X-ray exposure. On the other hand, X-ray exposure did increase other nuclear alterations closely related to cytotoxicity, such as karyorrhexis, pyknosis, and karyolysis. It seems that cigarette smoke did not affect X-ray outcomes induced in buccal cells.
conclusionThese data indicate that dental panoramic radiography may not induce chromosomal damage, but it is able to promote cytotoxicity. Because cellular death is considered a prime mechanism in nongenotoxic mechanisms of carcinogenesis, dental X-ray should be used only when necessary.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.