ArticleEuropean journal of applied physiology2008
Long-term resistance training improves force and unloaded shortening velocity of single muscle fibres of elderly women.
Article in European journal of applied physiology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.
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Who cites it
14 citing papers in PubMed, 2 syntheses or guidelines pooled it, 40 citations in OpenAlex.
- Improvements in skeletal muscle fiber size with resistance training are age-dependent in older adults: a systematic review and meta-analysis.Journal of applied physiology (Bethesda, Md. : 1985) · 2020Pooled it
- Resistance training induced changes in strength and specific force at the fiber and whole muscle level: a meta-analysis.European journal of applied physiology · 2019Pooled it
- Bioelectrical impedance phase angle is associated with physical performance before but not after simulated multi-stressor military operations.Physiological reports · 2023Trial
- Effects of high- and low-velocity resistance training on the contractile properties of skeletal muscle fibers from young and older humans.Journal of applied physiology (Bethesda, Md. : 1985) · 2011Trial
- Optimizing Resistance Training for Sprint and Endurance Athletes: Balancing Positive and Negative Adaptations.Sports medicine (Auckland, N.Z.) · 2024Review
- Influence of weighted downhill running training on serial sarcomere number and work loop performance in the rat soleus.Biology open · 2022Article
- Skeletal Muscle Quality: A Biomarker for Assessing Physical Performance Capabilities in Young Populations.Frontiers in physiology · 2021Review
- Musculoskeletal adaptations to strength training in frail elderly: a matter of quantity or quality?Journal of cachexia, sarcopenia and muscle · 2020Article
- Exercise-Induced Myofibrillar Hypertrophy is a Contributory Cause of Gains in Muscle Strength.Sports medicine (Auckland, N.Z.) · 2019Article
- Differential impact of tongue exercise on intrinsic lingual muscles.The Laryngoscope · 2018Article
- Moderate-intensity resistance exercise alters skeletal muscle molecular and cellular structure and function in inactive older adults with knee osteoarthritis.Journal of applied physiology (Bethesda, Md. : 1985) · 2017Article
- Article
- Biomechanical implications of skeletal muscle hypertrophy and atrophy: a musculoskeletal model.PeerJ · 2015Article
- Skeletal muscle myofilament adaptations to aging, disease, and disuse and their effects on whole muscle performance in older adult humans.Frontiers in physiology · 2014Review
Corrections and comments
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Authors and funding
7 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Four elderly women (78 +/- 4.3 years) were resistance trained (RT) for one year and needle biopsies of the vastus lateralis muscle were taken pre- and post-RT. A training intensity of 60% one-repetition maximum (1RM) was adopted for the entire duration of the study. Following RT, significant gain in isometric force of the quadriceps muscles was observed and MHC isoform distribution of vastus lateralis muscle showed a very significant shift from MHC-1 and MHC-2X towards MHC-2A, i.e. a bi-directional shift. A large population (n = 310) of individual skinned muscle fibres were dissected from biopsy samples and used for determination of cross-sectional area (CSA), specific force (Po/CSA) and unloaded shortening velocity (Vo) at 12 degrees C and maximum activation. Fibres were classified on the basis of their MHC isoform content determined by SDS-PAGE in three pure fibre types (1, 2A and 2X) and two hybrid fibre types (1-2A and 2AX). Whereas the CSA of individual muscle fibres did not change, Po/CSA was significantly higher in both type 1 and type 2A fibres post training. Vo of type 1 fibres was significantly higher post-training, whereas no change in Vo was observed in type 2A fibres. The number of pure type 2X fibres was very low especially post-training and did not enable a statistically significant comparison. The data suggest that in elderly women moderate and prolonged RT: (1) can determine similar adaptations in MHC distribution of skeletal muscle to those expected in young subjects; (2) can improve function of muscle fibres.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.