ArticleJournal of molecular biology2008
Transposition of Mboumar-9: identification of a new naturally active mariner-family transposon.
Article in Journal of molecular biology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
24 citing papers in PubMed, 51 citations in OpenAlex.
- Aphids and Ants, Mutualistic Species, Share aGenes · 2021Article
- Complex Evolutionary History of Mboumar, a Mariner Element Widely Represented in Ant Genomes.Scientific reports · 2020Article
- Targeted DNA transposition in vitro using a dCas9-transposase fusion protein.Nucleic acids research · 2019Article
- An Analysis of IS630/Tc1/mariner Transposons in the Genome of a Pacific Oyster, Crassostrea gigas.Journal of molecular evolution · 2018Article
- Genome-wide identification and evolution of TC1/Mariner in the silkworm (Bombyx mori) genome.Genes & genomics · 2018Article
- Diversity and evolution of mariner-like elements in aphid genomes.BMC genomics · 2017Article
- Characterization of irritans mariner-like elements in the olive fruit fly Bactrocera oleae (Diptera: Tephritidae): evolutionary implications.Die Naturwissenschaften · 2016Article
- Tc1-like Transposase Thm3 of Silver Carp (Hypophthalmichthys molitrix) Can Mediate Gene Transposition in the Genome of Blunt Snout Bream (Megalobrama amblycephala).G3 (Bethesda, Md.) · 2015Article
- Evolutionary history of the Azteca-like mariner transposons and their host ants.Die Naturwissenschaften · 2015Article
- Characterization of mariner-like transposons of the mauritiana Subfamily in seven tree aphid species.Genetica · 2015Article
- Biochemical characterization and comparison of two closely related active mariner transposases.Biochemistry · 2014Article
- Hyperactive mariner transposons are created by mutations that disrupt allosterism and increase the rate of transposon end synapsis.Nucleic acids research · 2014Article
- The ant genomes have been invaded by several types of mariner transposable elements.Die Naturwissenschaften · 2012Article
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- The transposon-like Correia elements encode numerous strong promoters and provide a potential new mechanism for phase variation in the meningococcus.PLoS genetics · 2011Article
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- Review
- Delivering the goods: viral and non-viral gene therapy systems and the inherent limits on cargo DNA and internal sequences.Genetica · 2010Review
- DNA transposons: nature and applications in genomics.Current genomics · 2010Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
Abstract
Although mariner transposons are widespread in animal genomes, the vast majority harbor multiple inactivating mutations and only two naturally occurring elements are known to be active. Previously, we discovered a mariner-family transposon, Mboumar, in the satellite DNA of the ant Messor bouvieri. Several copies of the transposon contain a full-length open reading frame, including Mboumar-9, which has 64% nucleotide identity to Mos1 of Drosophila mauritiana. To determine whether Mboumar is currently active, we expressed and purified the Mboumar-9 transposase and demonstrate that it is able to catalyze the movement of a transposon from one plasmid to another in a genetic in vitro hop assay. The efficiency is comparable to that of the well-characterized mariner transposon Mos1. Transposon insertions were precise and were flanked by TA duplications, a hallmark of mariner transposition. Mboumar has been proposed to have a role in the evolution and maintenance of satellite DNA in M. bouvieri and its activity provides a means to examine the involvement of the transposon in the genome dynamics of this organism.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.