Evidence map›Paper›PMID 18673490›Full record

ReviewNutrition reviews2008

Epigenetic regulation of chromatin structure and gene function by biotin: are biotin requirements being met?

Janos Zempleni, Yap Ching Chew, Yousef I Hassan, Subhashinee S K Wijeratne

Open access · bronzeAbstract readReview
In one paragraph

Review in Nutrition reviews, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.1field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Janos ZempleniThe Department of Nutrition and Health Sciences, University of Nebraska-Lincoln, Lincoln, Nebraska 68583-0806, USA. jzempleni2@unl.edu
Yap Ching Chew
Yousef I Hassan
Subhashinee S K Wijeratne
University of Nebraska–Lincoln · US

Funding

Vitamin-dependent modifications of histonesR01DK063945 · NIDDK · UNIVERSITY OF NEBRASKA LINCOLN · PI ZEMPLENI, JANOS · 2004 to 2011
$2.3M
Epigenetic effects of biotin on activation of endogenous viral sequencesR21ES015206 · NIEHS · UNIVERSITY OF NEBRASKA LINCOLN · PI ZEMPLENI, JANOS · 2006 to 2007
$396k
NIDDK NIH HHS DK 063945NIDDK NIH HHS R01 DK063945NIEHS NIH HHS ES 015206NIEHS NIH HHS R21 ES015206
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsBiotinBiotinylationCarbon-Nitrogen LigasesChromatinDietary SupplementsEpigenesis, GeneticFemaleHistonesHumansPregnancyBiotinCarbon-Nitrogen LigasesChromatinHistonesholocarboxylase synthetases

Identifiers

PMID18673490
PMCPMC2562292
OpenAlexW1883307906

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.