Evidence map›Paper›PMID 18672141›Full record

ReviewThe Surgical clinics of North America2008

Hamartomatous polyposis syndromes.

Daniel Calva, James R Howe

Open access · greenAbstract readReview
In one paragraph

Review in The Surgical clinics of North America, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed, 2 pooled it
5.9field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 2 syntheses or guidelines pooled it, 137 citations in OpenAlex.

  1. A systematic review of symptomatic hamartomas of the jejunum and ileum.Annals of the Royal College of Surgeons of England · 2022
    Pooled it
  2. Guideline
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. A NewDiagnostics (Basel, Switzerland) · 2022
    Article
  9. Review
  10. Article
  11. Article
  12. Review
  13. Observational
  14. Review
  15. Article
  16. Article
  17. Review
  18. Familial Colorectal Cancer: Understanding the Alphabet Soup.Clinics in colon and rectal surgery · 2016
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Daniel CalvaUniversity of Iowa, Roy J. and Lucille A. Carver College of Medicine, 200 Hawkins Drive, Iowa City, IA 52242-2600, USA.
James R Howe
University of Iowa · US

Funding

The Molecular Basis of Juvenile PolyposisR01CA098193 · NCI · UNIVERSITY OF IOWA · PI HOWE, JAMES R · 2003 to 2005
$788k
NCI NIH HHS R01 CA098193
6 · The paper itself

Abstract

Since the histologic description of the hamartomatous polyp in 1957 by Horrilleno and colleagues, descriptions have appeared of several different syndromes with the propensity to develop these polyps in the upper and lower gastrointestinal tracts. These syndromes include juvenile polyposis, Peutz-Jeghers syndrome, hereditary mixed polyposis syndrome, and the phosphatase and tensin homolog gene (PTEN) hamartoma tumor syndromes (Cowden and Bannayan-Riley-Ruvalcaba syndromes), which are autosomal-dominantly inherited, and Cronkhite-Canada syndrome, which is acquired. This article reviews the clinical aspects, the molecular pathogenesis, the affected organ systems, the risks of cancer, and the management of these hamartomatous polyposis syndromes. Although the incidence of these syndromes is low, it is important for clinicians to recognize these disorders to prevent morbidity and mortality in these patients, and to perform presymptomatic testing in patients at risk.

Indexed as

Genetic Predisposition to DiseasePeutz-Jeghers SyndromeDiagnosis, DifferentialDigestive System Surgical ProceduresEndoscopy, GastrointestinalHumansPrognosis

Identifiers

PMID18672141
PMCPMC2659506
OpenAlexW2032929912

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.