Evidence map›Paper›PMID 18672088›Full record

ReviewMicrobes and infection2008

Histoplasma capsulatum at the host-pathogen interface.

Joshua D Nosanchuk, Attila Gacser

Open access · greenAbstract readReview
In one paragraph

Review in Microbes and infection, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.0field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 42 citations in OpenAlex.

  1. Pulmonary Histoplasmosis: A Clinical Update.Journal of fungi (Basel, Switzerland) · 2023
    Review
  2. Review
  3. Histoplasma Capsulatum: Mechanisms for Pathogenesis.Current topics in microbiology and immunology · 2019
    Review
  4. Article
  5. Article
  6. An unusual cause of fever in a patient with common variable immunodeficiency.Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology · 2017
    Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Joshua D NosanchukDepartment of Medicine, Albert Einstein College of Medicine, Bronx, NY 10461, USA. nosanchu@aecom.yu.edu
Attila Gacser
Albert Einstein College of Medicine · USUniversity of Szeged · HU

Funding

Antibody Protection in HistoplamosisR01AI056070 · NIAID · ALBERT EINSTEIN COL OF MED YESHIVA UNIV · PI NOSANCHUK, JOSHUA D · 2005 to 2009
$1.8M
NIAID NIH HHS AI056070-01A2NIAID NIH HHS R01 AI056070
6 · The paper itself

Abstract

Histoplasma capsulatum is the most common cause of invasive fungal pulmonary disease worldwide. The interaction of H. capsulatum with a host is a complex, dynamic process. Severe disease most commonly occurs in individuals with compromised immunity, and the increasing utilization of immunomodulators in medicine has revealed significant risks for reactivation disease in patients with latent histoplasmosis. Fortunately, there are well developed molecular tools and excellent animal models for studying H. capsulatum virulence and numerous recent advances have been made regarding the pathogenesis of this fungus that will improve our capacity to combat disease.

Indexed as

Antibodies, MonoclonalDatabases, GeneticFungal VaccinesHistoplasmaHistoplasmosisHost-Pathogen InteractionsHumansAntibodies, MonoclonalFungal Vaccines

Identifiers

PMID18672088
PMCPMC2586805
OpenAlexW1963747907

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.