Evidence map›Paper›PMID 18671770›Full record

ArticleValue in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research

Economic evaluation of influenza pandemic mitigation strategies in the United States using a stochastic microsimulation transmission model.

Beate Sander, Azhar Nizam, Louis P Garrison, Maarten J Postma, M Elizabeth Halloran, Ira M Longini

Abstract readComparative Study
In one paragraph

Article in Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
61citing papers in PubMed, 7 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

61 citing papers in PubMed, 7 syntheses or guidelines pooled it.

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  8. Article
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  13. Assessing the Impacts of COVID-19 on the Industrial Sectors and Economy of China.Risk analysis : an official publication of the Society for Risk Analysis · 2022
    Review
  14. Economic impact of acute respiratory disease pandemics: A scoping review.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2022
    Article
  15. Article
  16. Coronavirus Disease 2019, School Closures, and Children's Mental Health.Soa--ch'ongsonyon chongsin uihak = Journal of child & adolescent psychiatry · 2020
    Article
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1 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Beate SanderDepartment of Health Policy, Management and Evaluation, University of Toronto, Canada. bsander@uhnres.utoronto.ca
Azhar Nizam
Louis P Garrison
Maarten J Postma
M Elizabeth Halloran
Ira M Longini

Funding

Containing Bioterrorist and Emerging Infectious DiseasesU01GM070749 · NIGMS · FRED HUTCHINSON CANCER RESEARCH CENTER · PI HALLORAN, M ELIZABETH, LONGINI, IRA M · 2004 to 2013
$8.3M
NIGMS NIH HHS U01 GM070749NIGMS NIH HHS U01-GM070749
6 · The paper itself

Abstract

objectivesTo project the potential economic impact of pandemic influenza mitigation strategies from a societal perspective in the United States.

methodsWe use a stochastic agent-based model to simulate pandemic influenza in the community. We compare 17 strategies: targeted antiviral prophylaxis (TAP) alone and in combination with school closure as well as prevaccination.

resultsIn the absence of intervention, we predict a 50% attack rate with an economic impact of $187 per capita as loss to society. Full TAP (FTAP) is the most effective single strategy, reducing number of cases by 54% at the lowest cost to society ($127 per capita). Prevaccination reduces number of cases by 48% and is the second least costly alternative ($140 per capita). Adding school closure to FTAP or prevaccination further improves health outcomes but increases total cost to society by approximately $2700 per capita.

conclusionFTAP is an effective and cost-saving measure for mitigating pandemic influenza.

Indexed as

Computer SimulationDisease OutbreaksStochastic ProcessesAntiviral AgentsCost-Benefit AnalysisCost SavingsHumansInfluenza, HumanModels, BiologicalModels, EconomicPublic HealthQuality-Adjusted Life YearsQuality of LifeUnited StatesAntiviral Agents

Identifiers

PMID18671770
PMCPMC3710126

What OpenQuestion holds

Textmetadata
LicenceTDM
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.