Evidence map›Paper›PMID 18671237›Full record

ArticleCytometry. Part A : the journal of the International Society for Analytical Cytology2008

Please do not disturb: destruction of chromatin structure by supravital nucleic acid probes revealed by a novel assay of DNA-histone interaction.

Donald Wlodkowic, Zbigniew Darzynkiewicz

Open access · bronzeAbstract readComment
In one paragraph

Article in Cytometry. Part A : the journal of the International Society for Analytical Cytology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Real-time cytotoxicity assays.Methods in molecular biology (Clifton, N.J.) · 2011
    Article
  6. Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Donald WlodkowicDepartment of Biological Sciences, Glasgow Caledonian University, Glasgow, G4 0BA, United Kingdom. donald.wlodkowic@cytotech.co.uk
Zbigniew Darzynkiewicz
New York Medical College · USNIHR MindTech MedTech Co-operative · GB

Funding

PROBES FOR FLOW CYTOMETRYR01CA028704 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI DARZYNKIEWICZ, ZBIGNIEW · 1985 to 2014
$6.0M
NCI NIH HHS R01 CA028704
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnthraquinonesChromatinDNADNA ProbesFluorescent DyesHeLa CellsHistonesHumansIntercalating AgentsStaining and Labeling1,5-bis((2-(methylamino)ethyl)amino)-4,8-dihydroxyanthracene-9,10-dioneAnthraquinonesChromatinDNADNA ProbesFluorescent DyesHistonesIntercalating Agents

Identifiers

PMID18671237
PMCPMC2617724
OpenAlexW1965917966

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.