ArticleProgress in polymer science2007
Smart Polymeric Gels: Redefining the Limits of Biomedical Devices.
Article in Progress in polymer science, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
56 citing papers in PubMed, 614 citations in OpenAlex.
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- Hydrogel-Based Vitreous Substitutes.International journal of molecular sciences · 2025Review
- Bioresorbable, wireless, passive sensors for continuous pH measurements and early detection of gastric leakage.Science advances · 2024Article
- Multi-stimuli-responsive Hydrogels for Therapeutic Systems: An Overview on Emerging Materials, Devices, and Drugs.Current pharmaceutical design · 2024Review
- Review
- Temperature-Sensitive Hydrogels as Carriers for Modulated Delivery of Acetaminophen.Gels (Basel, Switzerland) · 2023Article
- A Review of Research Progress on the Performance of Intelligent Polymer Gel.Molecules (Basel, Switzerland) · 2023Review
- Article
- Fabrication of Thermo-Responsive Controllable Shape-Changing Hydrogel.Gels (Basel, Switzerland) · 2022Article
- Mechanically Diverse Gels with Equal Solvent Content.ACS central science · 2022Article
- Cross-Linking Agents for Electrospinning-Based Bone Tissue Engineering.International journal of molecular sciences · 2022Review
- Surface Reconstruction of Fluoropolymers in Liquid Media.Langmuir : the ACS journal of surfaces and colloids · 2022Article
- Photoresponsive Gelation of Four-Armed Poly(ethylene glycol) with Photodimerizable Groups.Gels (Basel, Switzerland) · 2022Article
- Biomedical Application, Patent Repository, Clinical Trial and Regulatory Updates on Hydrogel: An Extensive Review.Gels (Basel, Switzerland) · 2021Review
- Exchange Counterion in Polycationic Hydrogels: Tunability of Hydrophobicity, Water State, and Floating Capability for a Floating pH Device.Gels (Basel, Switzerland) · 2021Article
- Protein Hydrogels: The Swiss Army Knife for Enhanced Mechanical and Bioactive Properties of Biomaterials.Nanomaterials (Basel, Switzerland) · 2021Review
- Microstructured Macromaterials Based on IPN Microgels.Polymers · 2021Article
- Semi-Crystalline Copolymer Hydrogels as Smart Drug Carriers: In Vitro Thermo-Responsive Naproxen Release Study.Pharmaceutics · 2021Article
- Hyaluronic Acid/Alginate Hydrogel Containing Hepatocyte Growth Factor and Promotion of Vocal Fold Wound Healing.Tissue engineering and regenerative medicine · 2020Article
- New Developments in Medical Applications of Hybrid Hydrogels Containing Natural Polymers.Molecules (Basel, Switzerland) · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
Abstract
This review describes recent progresses in the development and applications of smart polymeric gels, especially in the context of biomedical devices. The review has been organized into three separate sections: defining the basis of smart properties in polymeric gels; describing representative stimuli to which these gels respond; and illustrating a sample application area, namely, microfluidics. One of the major limitations in the use of hydrogels in stimuli-responsive applications is the diffusion rate limited transduction of signals. This can be obviated by engineering interconnected pores in the polymer structure to form capillary networks in the matrix and by downscaling the size of hydrogels to significantly decrease diffusion paths. Reducing the lag time in the induction of smart responses can be highly useful in biomedical devices, such as sensors and actuators. This review also describes molecular imprinting techniques to fabricate hydrogels for specific molecular recognition of target analytes. Additionally, it describes the significant advances in bottom-up nanofabrication strategies, involving supramolecular chemistry. Learning to assemble supramolecular structures from nature has led to the rapid prototyping of functional supramolecular devices. In essence, the barriers in the current performance potential of biomedical devices can be lowered or removed by the rapid convergence of interdisciplinary technologies.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.