ArticleGenome research2008
Relaxation of yeast mitochondrial functions after whole-genome duplication.
Article in Genome research, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed.
- Mitochondrial Genome Diversity across the Subphylum Saccharomycotina.bioRxiv : the preprint server for biology · 2023Article
- Mitochondrial genome diversity across the subphylum Saccharomycotina.Frontiers in microbiology · 2023Article
- From Genome Variation to Molecular Mechanisms: What we Have Learned From Yeast Mitochondrial Genomes?Frontiers in microbiology · 2022Review
- Codon usage bias and environmental adaptation in microbial organisms.Molecular genetics and genomics : MGG · 2021Article
- Discordant evolution of mitochondrial and nuclear yeast genomes at population level.BMC biology · 2020Article
- Genetic Drift and Indel Mutation in the Evolution of Yeast Mitochondrial Genome Size.Genome biology and evolution · 2017Article
- Article
- Ongoing resolution of duplicate gene functions shapes the diversification of a metabolic network.eLife · 2016Article
- Comparative Genomics of Sibling Fungal Pathogenic Taxa Identifies Adaptive Evolution without Divergence in Pathogenicity Genes or Genomic Structure.Genome biology and evolution · 2015Article
- Population structure of mitochondrial genomes in Saccharomyces cerevisiae.BMC genomics · 2015Article
- Article
- Identifying cis-regulatory changes involved in the evolution of aerobic fermentation in yeasts.Genome biology and evolution · 2013Article
- Yeast "make-accumulate-consume" life strategy evolved as a multi-step process that predates the whole genome duplication.PloS one · 2013Article
- Mitochondrial genome evolution in a single protoploid yeast species.G3 (Bethesda, Md.) · 2012Article
- Variation in global codon usage bias among prokaryotic organisms is associated with their lifestyles.Genome biology · 2011Article
- The mitochondrial genome sequence of the ciliate Paramecium caudatum reveals a shift in nucleotide composition and codon usage within the genus Paramecium.BMC genomics · 2011Article
- Determinants of translation efficiency and accuracy.Molecular systems biology · 2011Review
- Expansion of hexose transporter genes was associated with the evolution of aerobic fermentation in yeasts.Molecular biology and evolution · 2011Article
- Parallel evolution of the make-accumulate-consume strategy in Saccharomyces and Dekkera yeasts.Nature communications · 2011Article
- Tinkering evolution of post-transcriptional RNA regulons: puf3p in fungi as an example.PLoS genetics · 2010Article
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Mitochondria are essential for cellular energy production in most eukaryotic organisms. However, when glucose is abundant, yeast species that underwent whole-genome duplication (WGD) mostly conduct fermentation even under aerobic conditions, and most can survive without a functional mitochondrial genome. In this study, we show that the rate of evolution for the nuclear-encoded mitochondrial genes was greater in post-WGD species than pre-WGD species. Furthermore, codon usage bias was relaxed for these genes in post-WGD yeast species. The codon usage pattern and the distribution of a particular transcription regulatory element suggest that the change to an efficient aerobic fermentation lifestyle in this lineage might have emerged after WGD between the divergence of Kluyveromyces polysporus and Saccharomyces castellii from their common ancestor. This new energy production strategy could have led to the relaxation of mitochondrial function in the relevant yeast species.
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