ReviewSurgery today2008
Primary small-cell neuroendocrine carcinoma of the breast: report of a case.
Review in Surgery today, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 46 citations in OpenAlex.
- Epidemiology, Treatment and Prognosis Analysis of Small Cell Breast Carcinoma: A Population-Based Study.Frontiers in endocrinology · 2022Trial
- Mammary small cell neuroendocrine carcinomas that showed excellent pathologic response following etoposide-based neoadjuvant chemotherapy.Breast cancer research and treatment · 2025Article
- Organoids as a model system for researching human neuroendocrine tumor of the breast.Cancer cell international · 2024Article
- Primary Small Cell Carcinoma of the Breast: An Approach to Medical and Surgical Management.Cureus · 2023Article
- Primary neuroendocrine carcinoma of the breast with leptomeninges metastasis: A case report and literature review.The Journal of international medical research · 2022Review
- TTF-1 Positive Primary Small Cell Carcinoma of the Breast: A Case Report and Review of the Literature.Frontiers in endocrinology · 2020Review
- Rare epithelial breast cancer: surgery and adjuvant therapy.Translational cancer research · 2019Review
- Triple receptor-positive primary neuroendocrine carcinoma of breast in a young patient.BMJ case reports · 2018Article
- Primary Neuroendocrine Breast Carcinoma in a 13-Year-Old Girl: Ultrasonography and Pathology Findings.Case reports in radiology · 2017Article
- Primary Neuroendocrine Carcinoma of the Breast: Histopathological Criteria, Prognostic Factors, and Review of the Literature.Case reports in pathology · 2016Article
- Primary Neuroendocrine Carcinoma of the Breast: A Report of Three Cases.The journal of breast health · 2014Article
- Multidisciplinary management of small cell carcinoma of the breast: a case report.Nagoya journal of medical science · 2014Article
- Neuroendocrine carcinoma of breast: a rare case vignette.Journal of clinical and diagnostic research : JCDR · 2013Article
- Locally-advanced primary neuroendocrine carcinoma of the breast: case report and review of the literature.World journal of surgical oncology · 2013Article
- Case report of primary small cell neuroendocrine breast cancer.Clujul medical (1957) · 2013Article
- A rare case of primary infiltrating neuroendocrine carcinoma of the breast.Iranian journal of radiology : a quarterly journal published by the Iranian Radiological Society · 2012Article
- A case report of primary small cell carcinoma of the breast and review of the literature.Chinese journal of cancer · 2012Review
- Small-cell neuroendocrine carcinoma of the breast.Journal of the Korean Surgical Society · 2012Article
- Management of neuroendocrine carcinomas of the breast: A rare entity.Oncology letters · 2011Article
- Primary small cell carcinoma of the breast with TTF-1 and neuroendocrine marker expressing carcinoma in situ.International journal of clinical and experimental pathology · 2010Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Primary small-cell neuroendocrine carcinoma of the breast is a rare and aggressive neoplasm without an established treatment protocol because so few cases have been described. We report a case of primary small-cell neuroendocrine carcinoma in a 31-year-old woman. The patient came to our hospital 10 days after consulting another clinic, where a diagnosis of locally advanced breast cancer suitable for neoadjuvant chemotherapy had been made. Core needle biopsy under ultrasonographic guidance revealed invasive carcinoma. The doubling time of the tumor progression was calculated as 12 days based on ultrasonographic measurement. After three cycles of chemotherapeutic regimens consisting of adriamycin plus docetaxel, the disease was judged to be progressive and the patient underwent surgery. Definitive histopathological examination revealed primary small-cell neuroendocrine carcinoma. Local and mediastinal recurrence with multiple liver metastases developed only 5 weeks after surgery. Cisplatin plus irinotecan combination chemotherapy was started; however, the patient died of aggressive recurrent tumor progression 6 months after surgery, in spite of the transient tumor regression achieved by chemotherapy. This case reinforces the importance of an early correct diagnosis and the standardization of a treatment regimen for this very rare tumor.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.