ArticleApplied microbiology and biotechnology2008
Comparative metabolomic analysis of Sinorhizobium sp. C4 during the degradation of phenanthrene.
Article in Applied microbiology and biotechnology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
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Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 84 citations in OpenAlex.
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- Pseudomonas aeruginosa PR23 isolated from oil contaminated soil tolerate and degrades mixture of polyaromatic hydrocarbons and express novel proteins.World journal of microbiology & biotechnology · 2024Article
- Oil Bioremediation in the Marine Environment of Antarctica: A Review and Bibliometric Keyword Cluster Analysis.Microorganisms · 2021Review
- Omics Approaches to Pesticide Biodegradation.Current microbiology · 2020Review
- Exo-Metabolites ofMetabolites · 2019Article
- Understanding and Designing the Strategies for the Microbe-Mediated Remediation of Environmental Contaminants Using Omics Approaches.Frontiers in microbiology · 2018Review
- Engineering a bzd cassette for the anaerobic bioconversion of aromatic compounds.Microbial biotechnology · 2017Article
- Current State of Knowledge in Microbial Degradation of Polycyclic Aromatic Hydrocarbons (PAHs): A Review.Frontiers in microbiology · 2016Review
- Microbial community structure and dynamics in a membrane bioreactor supplemented with the flame retardant dibromoneopentyl glycol.Environmental science and pollution research international · 2015Article
- Metabolomics reveals differences of metal toxicity in cultures of Pseudomonas pseudoalcaligenes KF707 grown on different carbon sources.Frontiers in microbiology · 2015Article
- Comparison of phenanthrene biodegradation by free and immobilized cell systems: formation of hydroxylated compounds.Environmental science and pollution research international · 2014Article
- Article
- Metabolomic and proteomic insights into carbaryl catabolism by Burkholderia sp. C3 and degradation of ten N-methylcarbamates.Biodegradation · 2013Article
- Ecogenomics of microbial communities in bioremediation of chlorinated contaminated sites.Frontiers in microbiology · 2012Article
- Soybean metabolites regulated in root hairs in response to the symbiotic bacterium Bradyrhizobium japonicum.Plant physiology · 2010Article
- Bacterial degradation of aromatic compounds.International journal of environmental research and public health · 2009Review
Corrections and comments
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Authors and funding
4 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Comparative metabolic responses of Sinorhizobium sp. C4 were investigated. Comprehensive metabolites profiles, including polar metabolites, fatty acids, and polyhydroxyalkanoates were evaluated through untargeted metabolome analyses. Intracellular metabolomes during the degradation of phenanthrene were compared with those from natural carbon sources. Principal component analysis showed a clear separation of metabolomes of phenanthrene degradation from other carbon sources. Shift to more hydrophobic fatty acid was observed from the analysis of fatty acid methyl ester. Polyhydroxyalkanoate from strain C4 was composed mainly with 3-hydroxybutyric acid and small amount of 3-hydroxypentanoic acid, while the monomeric composition was independent on carbon sources. However, the amount of polyhydroxyalkanoates during degradation of phenanthrene was 50-210% less than those from other carbon sources. Among 207 gas chromatography-mass spectrometry peaks from the polar metabolite fraction, 60% of the peaks were identified and compared. Several intermediates in tricarboxylic acid cycles and glycolysis were increased during phenanthrene degradation. Accumulation of trehalose was also evident in the phenanthrene-treated bacterium. Some amino acid, including branched amino acids, glycine, homoserine, and valine, were also increased, while more than 70% of identified metabolites were decreased during the phenanthrene metabolism. Accumulation of sulfur amino acids and nicotinic acid suggested the possible oxidative stress conditions during phenanthrene metabolism.
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