ReviewKidney international2008
Neointimal hyperplasia associated with synthetic hemodialysis grafts.
Review in Kidney international, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
52 citing papers in PubMed, 1 synthesis or guideline pooled it, 127 citations in OpenAlex.
- Pooled it
- Randomized pilot study to compare metal needles versus plastic cannulae in the development of complications in hemodialysis access.The journal of vascular access · 2018Trial
- Impact of the drug-coated balloon-to-predilation balloon diameter ratio on restenosis risk in hemodialysis access: a study of nonlinear association.Renal failure · 2026Article
- Stem Cell Therapy: Past, Present, and Future Aspects.Biomedicines · 2026Review
- Programmable Compliance in Small-Diameter Vascular Grafts by Design of Melt-Electrowritten Scaffold Architectures for In Situ Tissue Engineering.Advanced healthcare materials · 2026Article
- Hemodialysis vascular access flow surveillance: Current evidence and future directions.Journal of the Chinese Medical Association : JCMA · 2025Review
- In Silico, Patient-Specific Assessment of Local Hemodynamic Predictors and Neointimal Hyperplasia Localisation in an Arteriovenous Graft.Annals of biomedical engineering · 2025Article
- Comparison of Helical Interwoven Nitinol Stent Placement Versus Balloon Angioplasty for Arteriovenous Dialysis Graft Malfunction Caused by Stenosis of the Venous Anastomosis Site.Journal of the Korean Society of Radiology · 2025Article
- Implantable Biosensors for Vascular Diseases: Directions for the Next Generation of Active Diagnostic and Therapeutic Medical Device Technologies.Biosensors · 2025Review
- Enhanced hemocompatibility and rapid magnetic anastomosis of electrospun small-diameter artificial vascular grafts.Frontiers in bioengineering and biotechnology · 2024Article
- Article
- Choosing the right treatment for the right lesion, part I: a narrative review of the role of plain balloon angioplasty in dialysis access maintenance.Cardiovascular diagnosis and therapy · 2023Review
- Rapid remodeling observed at mid-term in-vivo study of a smart reinforced acellular vascular graft implanted on a rat model.Journal of biological engineering · 2023Article
- Nanofiber-coated, tacrolimus-eluting sutures inhibit post-operative neointimal hyperplasia in rats.Journal of controlled release : official journal of the Controlled Release Society · 2023Article
- Personalized tissue-engineered arteries as vascular graft transplants: A safety study in sheep.Regenerative therapy · 2022Article
- Article
- Novel reinforcement of corrugated nanofiber tissue-engineered vascular graft to prevent aneurysm formation for arteriovenous shunts in an ovine model.JVS-vascular science · 2022Article
- Effect of pore size and spacing on neovascularization of a biodegradble shape memory polymer perivascular wrap.Journal of biomedical materials research. Part A · 2021Article
- Modifications of the mechanical properties of in vivo tissue-engineered vascular grafts by chemical treatments for a short duration.PloS one · 2021Article
- Cellular remodeling of fibrotic conduit as vascular graft.Biomaterials · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
Stenosis is a major cause of failure of hemodialysis vascular grafts and is primarily caused by neointimal hyperplasia (NH) at the anastomoses. The objective of this article is to provide a scientific review of the biology underlying this disorder and a critical review of the state-of-the-art investigational preventive strategies in order to stimulate further research in this exciting area. The histology of the NH shows myofibroblasts (that are probably derived from adventitial fibroblasts), extracellular matrices, pro-inflammatory cells including foreign-body giant cells, a variety of growth factors and cytokines, and neovasculature. The contributing factors of the pathogenesis of NH include surgical trauma, bioincompatibility of the synthetic graft, and the various mechanical stresses that result from luminal hypertension and compliance mismatch between the vessel wall and graft. These mechanical stimuli are focal in nature and may have a significant influence on the preferential localization of the NH. Novel mechanical graft designs and local drug delivery strategies show promise in animal models in preventing graft NH development. Successful prevention of graft stenosis would provide a superior alternative to the native fistula as hemodialysis vascular access.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.