Evidence map›Paper›PMID 18667346›Full record

ArticleJournal of magnetic resonance (San Diego, Calif. : 1997)2008

Regularized optimization (RO) reconstruction for oximetric EPR imaging.

Mark Tseitlin, Tomasz Czechowski, Sandra S Eaton, Gareth R Eaton

Abstract read
In one paragraph

Article in Journal of magnetic resonance (San Diego, Calif. : 1997), 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Accelerated EPR imaging using deep learning denoising.Magnetic resonance in medicine · 2025
    Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Deconvolution of sinusoidal rapid EPR scans.Journal of magnetic resonance (San Diego, Calif. : 1997) · 2011
    Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Mark TseitlinDepartment of Chemistry and Biochemistry, University of Denver, Denver, CO 80208, USA.
Tomasz Czechowski
Sandra S Eaton
Gareth R Eaton

Funding

Rapid Scan Biomedical EPR Spectroscopy and ImagingR01EB000557 · NIBIB · UNIVERSITY OF DENVER (COLORADO SEMINARY) · PI EATON, GARETH R · 2002 to 2011
$4.0M
Rapid Scan Biomedical EPR Spectroscopy and ImagingR56EB000557 · NIBIB · UNIVERSITY OF DENVER (COLORADO SEMINARY) · PI EATON, GARETH R · 2007 to 2007
$494k
NIBIB NIH HHS EB000557NIBIB NIH HHS R01 EB000557NIBIB NIH HHS R56 EB000557
6 · The paper itself

Abstract

A new algorithm for EPR imaging oximetry is described and tested with experimental data for the case of one spatial and one spectral dimension. A single species with variable linewidth is assumed. Instead of creating a 2D image, two one-dimensional profiles are reconstructed: the concentration of the radical and the corresponding oxygen concentration, which reduces the dimensionality of the problem. The algorithm (i) seeks to minimize the discrepancy between experimental data and projections calculated from the profiles and (ii) uses Tikhonov regularization to constrain the smoothness of the results. This approach controllably smoothes profiles rather than the data, while preserving sharp features.

Indexed as

AlgorithmsElectron Spin Resonance SpectroscopyImage Interpretation, Computer-AssistedOximetryOxygenReproducibility of ResultsSensitivity and SpecificityOxygen

Identifiers

PMID18667346
PMCPMC3419263

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.