Evidence map›Paper›PMID 18665264›Full record

ArticlePloS one2008

High-resolution, in vivo magnetic resonance imaging of Drosophila at 18.8 Tesla.

Brian Null, Corey W Liu, Maj Hedehus, Steven Conolly, Ronald W Davis

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 31 citations in OpenAlex.

  1. Article
  2. Article
  3. Micro-computed tomography as a platform for exploringDevelopment (Cambridge, England) · 2019
    Article
  4. Article
  5. Article
  6. Physical principles for scalable neural recording.Frontiers in computational neuroscience · 2013
    Article
  7. Review
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Brian NullStanford Genome Technology Center/Department of Biochemistry/Bio-X Program, Stanford, California, United States of America. zenbonz@gmail.com
Corey W Liu
Maj Hedehus
Steven Conolly
Ronald W Davis
Resonance Research (United States) · USStanford Medicine · USUniversity of California, Berkeley · USVarian Medical Systems (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

High resolution MRI of live Drosophila was performed at 18.8 Tesla, with a field of view less than 5 mm, and administration of manganese or gadolinium-based contrast agents. This study demonstrates the feasibility of MR methods for imaging the fruit fly Drosophila with an NMR spectrometer, at a resolution relevant for undertaking future studies of the Drosophila brain and other organs. The fruit fly has long been a principal model organism for elucidating biology and disease, but without capabilities like those of MRI. This feasibility marks progress toward the development of new in vivo research approaches in Drosophila without the requirement for light transparency or destructive assays.

Indexed as

AnimalsBrainChloridesContrast MediaDevelopmental BiologyDrosophila melanogasterEquipment DesignFeasibility StudiesGadolinium DTPAImage Processing, Computer-AssistedMagnetic Resonance ImagingMagnetic Resonance SpectroscopyManganese CompoundsReproducibility of ResultsSoftwareChloridesContrast MediaGadolinium DTPAmanganese chlorideManganese Compounds

Identifiers

PMID18665264
PMCPMC2474967
OpenAlexW2008457031

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.