ArticleJournal of the American Geriatrics Society2008
Health outcome priorities among competing cardiovascular, fall injury, and medication-related symptom outcomes.
Article in Journal of the American Geriatrics Society, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 64 papers, 4 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
64 citing papers in PubMed, 4 syntheses or guidelines pooled it, 104 citations in OpenAlex.
- Pooled it
- Pooled it
- Systematic review of clinical practice guidelines recommendations about primary cardiovascular disease prevention for older adults.BMC family practice · 2015Pooled it
- Risk as an attribute in discrete choice experiments: a systematic review of the literature.The patient · 2014Pooled it
- Impact of Intensive Blood Pressure Therapy on Concern about Falling: Longitudinal Results from the Systolic Blood Pressure Intervention Trial (SPRINT).Journal of the American Geriatrics Society · 2020Trial
- Hypertension Treatment and Concern About Falling: Baseline Data from the Systolic Blood Pressure Intervention Trial.Journal of the American Geriatrics Society · 2016Trial
- Pre-Visit Prioritization for complex patients with diabetes: Randomized trial design and implementation within an integrated health care system.Contemporary clinical trials · 2016Trial
- Changes in cholesterol-lowering medications use over a decade in community-dwelling older adults.The Annals of pharmacotherapyTrial
- Fall Risk and Medication Use Near End of Life Among Adults With Chronic Obstructive Pulmonary Disease.Chronic obstructive pulmonary diseases (Miami, Fla.) · 2024Article
- Preferences of patients with multiple chronic diseases for medication in rural areas of an Eastern Province China: a discrete choice experiment.Frontiers in medicine · 2024Article
- European position paper on polypharmacy and fall-risk-increasing drugs recommendations in the World Guidelines for Falls Prevention and Management: implications and implementation.European geriatric medicine · 2023Article
- Preferences for deprescribing antihypertensive medications amongst clinicians, carers and people living with dementia: a discrete choice experiment.Age and ageing · 2023Article
- From precision medicine to precision care: Choosing and using precision medicine in the context of multimorbidity.Cambridge prisms. Precision medicine · 2023Review
- Beyond MACE: a multidimensional approach to outcomes in clinical trials for older adults with stable ischemic heart disease.Frontiers in cardiovascular medicine · 2023Review
- Knowledge, attitude and practice on fall risk factors and prevention among rural older community-dwellers in Vietnam.PloS one · 2023Article
- Association between willingness to deprescribe and health outcome priorities among U.S. older adults: Results of a national survey.Journal of the American Geriatrics Society · 2022Article
- Clinical outcomes of modifying hypertension treatment intensity in older adults treated to low blood pressure.Journal of the American Geriatrics Society · 2021Article
- Article
- Patient Perceptions and Familiarity With Medical Therapy for Heart Failure.JAMA cardiology · 2020Article
- Methods to Assess Patient Preferences in Old Age Pharmacotherapy - A Systematic Review.Patient preference and adherence · 2020Review
4 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 1 institution in 1 country.
Funding
Abstract
objectivesTo determine the priority that older adults with coexisting hypertension and fall risk give to optimizing cardiovascular outcomes versus fall- and medication symptom-related outcomes.
designInterview.
settingCommunity.
participantsOne hundred twenty-three cognitively intact persons aged 70 and older with hypertension and fall risk. MEASUREMENTS: Discrete choice task was used to elicit the relative importance placed on reducing the risk of three outcomes: cardiovascular events, serious fall injuries, and medication symptoms. Risk estimates with and without antihypertensive medications were obtained from the literature. Participants chose between 11 pairs of options that displayed lower risks for one or two outcomes and a higher risk for the other outcome(s), versus the reverse. Results were used to calculate relative importance scores for the three outcomes. These scores, which sum to 100, reflect the relative priority participants placed on the difference between the risk estimates of each outcome.
resultsSixty-two participants (50.4%) placed greater importance on reducing risk of cardiovascular events than reducing risk of the combination of fall injuries and medication symptoms; 61 participants did the converse. A lower percentage of participants with chronic obstructive pulmonary disease (P=.02), unsteadiness (P=.02), functional dependency (P=.04), lower cognition (P=.02) and depressive symptoms (P=.03) prioritized cardiovascular outcomes over fall injuries and medication symptoms than did participants without these characteristics.
conclusionInterindividual variability in the face of competing outcomes supports individualizing decision-making to individual priorities. In the current example, this may mean forgoing antihypertensive medications or compromising on blood pressure reduction for some individuals.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.