Evidence map›Paper›PMID 18661989›Full record

ArticleJournal of the American Chemical Society2008

Coupling across a DNA helical turn yields a hybrid DNA/organic catenane doubly tailed with functional termini.

Yu Liu, Akinori Kuzuya, Ruojie Sha, Johan Guillaume, Risheng Wang, James W Canary, Nadrian C Seeman

Abstract read
In one paragraph

Article in Journal of the American Chemical Society, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Solid Phase Stepwise Synthesis of Polyethylene Glycols.Chemistry (Weinheim an der Bergstrasse, Germany) · 2017
    Article
  6. Article
  7. Article
  8. Artificial Molecular Machines.Chemical reviews · 2015
    Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yu LiuDepartment of Chemistry, New York University, New York, New York 10003, USA.
Akinori Kuzuya
Ruojie Sha
Johan Guillaume
Risheng Wang
James W Canary
Nadrian C Seeman

Funding

Physical Chemistry of Recombinational IntermediatesR37GM029554 · NIGMS · NEW YORK UNIVERSITY · PI SEEMAN, NADRIAN C. · 2005 to 2012
$2.7M
PHYSICAL CHEMISTRY OF RECOMBINATIONAL INTERMEDIATESR01GM029554 · NIGMS · STATE UNIVERSITY OF NEW YORK AT ALBANY · PI SEEMAN, NADRIAN C. · 1985 to 2004
$1.4M
Fluorescent Probes for Manganese(II)R21GM076202 · NIGMS · NEW YORK UNIVERSITY · PI CANARY, JAMES W · 2006 to 2007
$379k
NIGMS NIH HHS GM-076202NIGMS NIH HHS GM-29554NIGMS NIH HHS R01 GM029554NIGMS NIH HHS R21 GM076202NIGMS NIH HHS R37 GM029554
6 · The paper itself

Abstract

We describe the synthesis of a hybrid DNA/organic macrocycle that is prepared by formation of an amide linkage across one full turn of DNA. Formation of a catenane proved that the linkage crossed a turn rather than running along the phosphodiester backbone contour. The product, a doubly tailed catenane, contains 5'- and 3'-termini that can be functionalized further or used to incorporate the catenane structure into other DNA assemblies.

Indexed as

AnthracenesDNAMolecular StructureNucleic Acid ConformationOligonucleotidesStereoisomerismUltraviolet RaysAnthracenescatenaneDNAOligonucleotides

Identifiers

PMID18661989
PMCPMC2712227

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.