ArticleAnnals of botany2009
Transcript and metabolite profiling of the adaptive response to mild decreases in oxygen concentration in the roots of arabidopsis plants.
Article in Annals of botany, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 81 papers.
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81 citing papers in PubMed, 227 citations in OpenAlex.
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- Metabolite Profiling of Leaves of Irises and Cinquefoils of Hydrophytic and Mesophytic Nature.International journal of molecular sciences · 2026Article
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- Recent progress in understanding the cellular and genetic basis of plant responses to low oxygen holds promise for developing flood-resilient crops.Journal of experimental botany · 2024Article
- Plant Life with and without Oxygen: A Metabolomics Approach.International journal of molecular sciences · 2023Review
- Preserving root stem cell functionality under low oxygen stress: the role of nitric oxide and phytoglobins.Planta · 2023Review
- Complexity of Abiotic Stress Stimuli: Mimicking Hypoxic Conditions Experimentally on the Basis of Naturally Occurring Environments.Methods in molecular biology (Clifton, N.J.) · 2023Article
- Metabolism and Signaling of Plant Mitochondria in Adaptation to Environmental Stresses.International journal of molecular sciences · 2022Review
- Physiological and comparative transcriptome analyses reveal the mechanisms underlying waterlogging tolerance in a rapeseed anthocyanin-more mutant.Biotechnology for biofuels and bioproducts · 2022Article
- Cereal Germination under Low Oxygen: Molecular Processes.Plants (Basel, Switzerland) · 2022Review
- Try or Die: Dynamics of Plant Respiration and How to Survive Low Oxygen Conditions.Plants (Basel, Switzerland) · 2022Review
- Sugar modulation of anaerobic-response networks in maize root tips.Plant physiology · 2021Article
- Primary Metabolite Adjustments Associated With Pinewood Nematode Resistance inFrontiers in plant science · 2021Article
- Transcriptome and metabolite profiling reveals the effects of Funneliformis mosseae on the roots of continuously cropped soybeans.BMC plant biology · 2020Article
- Metabolic Responses to Waterlogging Differ between Roots and Shoots and Reflect Phloem Transport Alteration inPlants (Basel, Switzerland) · 2020Article
- Overexpression ofPlants (Basel, Switzerland) · 2020Article
21 more citing papers are in PubMed but not listed here.
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10 authors at 1 institution in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND
aimsOxygen can fall to low concentrations within plant tissues, either because of environmental factors that decrease the external oxygen concentration or because the movement of oxygen through the plant tissues cannot keep pace with the rate of oxygen consumption. Recent studies document that plants can decrease their oxygen consumption in response to relatively small changes in oxygen concentrations to avoid internal anoxia. The molecular mechanisms underlying this response have not been identified yet. The aim of this study was to use transcript and metabolite profiling to investigate the genomic response of arabidopsis roots to a mild decrease in oxygen concentrations.
methodsArabidopsis seedlings were grown on vertical agar plates at 21, 8, 4 and 1 % (v/v) external oxygen for 0.5, 2 and 48 h. Roots were analysed for changes in transcript levels using Affymetrix whole genome DNA microarrays, and for changes in metabolite levels using routine GC-MS based metabolite profiling. Root extension rates were monitored in parallel to investigate adaptive changes in growth. KEY
resultsThe results show that root growth was inhibited and transcript and metabolite profiles were significantly altered in response to a moderate decrease in oxygen concentrations. Low oxygen leads to a preferential up-regulation of genes that might be important to trigger adaptive responses in the plant. A small but highly specific set of genes is induced very early in response to a moderate decrease in oxygen concentrations. Genes that were down-regulated mainly encoded proteins involved in energy-consuming processes. In line with this, root extension growth was significantly decreased which will ultimately save ATP and decrease oxygen consumption. This was accompanied by a differential regulation of metabolite levels at short- and long-term incubation at low oxygen.
conclusionsThe results show that there are adaptive changes in root extension involving large-scale reprogramming of gene expression and metabolism when oxygen concentration is decreased in a very narrow range.
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