Evidence map›Paper›PMID 18657920›Full record

ReviewExperimental gerontology

Age-related muscle dysfunction.

LaDora V Thompson

Abstract readReview
In one paragraph

Review in Experimental gerontology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 104 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
104citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

104 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Trial
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  7. Review
  8. Review
  9. High-Performance Dopamine-Based Supramolecular Bio-Adhesives.Macromolecular rapid communications · 2024
    Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Review
  15. Article
  16. Article
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  18. Article
  19. Age-Related Changes in Skeletal Muscle Oxygen Utilization.Journal of functional morphology and kinesiology · 2022
    Review
  20. Article

44 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

LaDora V ThompsonDepartment of Physical Medicine and Rehabilitation, University of Minnesota, MMC 388, 420 Delaware Street, S.E., Minneapolis, MN 55455, USA. thomp067@umn.edu

Funding

Structural and Calcium Regulatory Proteins in SarcopeniaR01AG017768 · NIA · UNIVERSITY OF MINNESOTA TWIN CITIES · PI THOMPSON, LADORA V · 2001 to 2012
$3.0M
NIA NIH HHS R01 AG017768
6 · The paper itself

Abstract

Aging is associated with a progressive decline of muscle mass, strength, and quality, a condition described as sarcopenia of aging. Despite the significance of skeletal muscle atrophy, the mechanisms responsible for the deterioration of muscle performance are only partially understood. The purpose of this review is to highlight cellular, molecular, and biochemical changes that contribute to age-related muscle dysfunction.

Indexed as

AgedAgingFemaleGene Expression RegulationHumansMaleMiddle AgedMitochondria, MuscleMuscle ProteinsMuscle, SkeletalMuscular AtrophyOxidative StressProtein Processing, Post-TranslationalMuscle Proteins

Identifiers

PMID18657920
PMCPMC4074082

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.