ArticleGraefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie2008
Comparison of visual function in pigmented and albino rats by electroretinography and visual evoked potentials.
Article in Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed.
- First record of albinism in the black-fronted titi monkey using a dual-sensor drone: an unprecedented case in Neotropical primates.Primates; journal of primatology · 2026Article
- Longitudinal retinal functional evaluation using full-field electroretinography in New Zealand white and Dutch Belted rabbits with aging.Scientific reports · 2025Article
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- The prion protein is required for normal responses to light stimuli by photoreceptors and bipolar cells.iScience · 2024Article
- Reduction of pathological retinal neovascularization, vessel obliteration, and artery tortuosity by PEDF protein in an oxygen-induced ischemic retinopathy rat model.FASEB bioAdvances · 2024Article
- The Future Is Not Bright: Evaluation of Rat Preferences for Color and Intensity of Light.Animals : an open access journal from MDPI · 2024Article
- ERG Responses in Albinism, Idiopathic Infantile Nystagmus, and Controls.Investigative ophthalmology & visual science · 2024Article
- Sex-related differences in retinal function in Wistar rats: implications for toxicity and safety studies.Frontiers in toxicology · 2023Article
- The impact of early-life environment on absence epilepsy and neuropsychiatric comorbidities.IBRO neuroscience reports · 2022Review
- First observation of a chimpanzee with albinism in the wild: Social interactions and subsequent infanticide.American journal of primatology · 2022Article
- Infra-slow modulation of fast beta/gamma oscillations in the mouse visual system.The Journal of physiology · 2021Article
- Challenging a Myth and Misconception: Red-Light Vision in Rats.Animals : an open access journal from MDPI · 2020Article
- Volumes of brain structures in captive wild-type and laboratory rats: 7T magnetic resonance in vivo automatic atlas-based study.PloS one · 2019Article
- Low-intensity repetitive transcranial magnetic stimulation requires concurrent visual system activity to modulate visual evoked potentials in adult mice.Scientific reports · 2018Article
- Comparison between albino and pigmented rabbit ERGs.Documenta ophthalmologica. Advances in ophthalmology · 2018Article
- Article
- Early applications of granulocyte colony-stimulating factor (G-CSF) can stabilize the blood-optic-nerve barrier and ameliorate inflammation in a rat model of anterior ischemic optic neuropathy (rAION).Disease models & mechanisms · 2016Article
- Visual Evoked Potential Recording in a Rat Model of Experimental Optic Nerve Demyelination.Journal of visualized experiments : JoVE · 2015Article
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Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo check differences in visual function between Wistar (albino) and Long-Evans (pigmented) rats.
methodsThe animals were born in our facilities and reared under identical light conditions avoiding bright light. Visual electrophysiology was performed at the ages of 1.5, 4, 7 and 10 months (electroretinography, ERG) and at 1.5 and 7 months (visual evoked potentials, VEP).
resultsERG measurements showed that: 1) The amplitudes of both scotopic and photopic b-waves were markedly larger in Long-Evans rats than in Wistar rats, and also the amplitudes of scotopic oscillatory potentials and photopic 30 Hz Flicker amplitudes, 2) scotopic a-wave amplitudes were larger in Wistar rats at low light intensities, whereas they were smaller in bright light, 3) both a-wave and b-wave latencies were shorter in Wistar rats, 4) the maximum response Rm(P3) was larger in Long-Evans rats, 5) the sensitivity parameter S was larger in Wistar rats, and 6) the post-receptoral response of cones was smaller in Wistar rats. In the VEP measurements, amplitudes of both photopic and scotopic visual evoked potentials of Long-Evans rats were only slightly larger than those of Wistar rats.
conclusionsERG b-wave amplitudes are markedly decreased in Wistar rats, which requires further investigation. As the b/a and OP/a ratios were also decreased in Wistar rats, it can be suggested that post-receptoral processing, in particular, is impaired in albino animals.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.