Evidence map›Paper›PMID 18654123›Full record

Trial reportAmerican journal of hypertension2008

A practice-based trial of motivational interviewing and adherence in hypertensive African Americans.

Gbenga Ogedegbe, William Chaplin, Antoinette Schoenthaler, David Statman, David Berger, Tabia Richardson, Erica Phillips, Jacqueline Spencer, John P Allegrante

Open access · bronzeAbstract readComparative StudyMulticenter StudyRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in American journal of hypertension, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 110 papers, 17 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
110citing papers in PubMed, 17 pooled it
5.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

110 citing papers in PubMed, 17 syntheses or guidelines pooled it, 199 citations in OpenAlex.

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  4. Motivational Interviewing in Ethnic Populations.Journal of immigrant and minority health · 2020
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  8. Interventions for enhancing medication adherence.The Cochrane database of systematic reviews · 2014
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  12. Interventions to increase medication adherence in African-American and Latino populations: a literature review.Hawai'i journal of medicine & public health : a journal of Asia Pacific Medicine & Public Health · 2014
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  17. Interventions to improve adherence and persistence with osteoporosis medications: a systematic literature review.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2009
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50 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Gbenga OgedegbeDepartment of Medicine, New York University School of Medicine, New York, New York, USA. olugbenga.ogedegbe@nyumc.org
William Chaplin
Antoinette Schoenthaler
David Statman
David Berger
Tabia Richardson
Erica Phillips
Jacqueline Spencer
John P Allegrante
St. John's University · USCornell University · USNew York University · USColumbia University · US

Funding

MULTI-SITE RCT FOR BP CONTROL IN HTN AFRICAN AMERICANSR01HL078566 · NHLBI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI OGEDEGBE, OLUGBENGA G. · 2004 to 2011
$4.5M
MIND-BODY-BEHAVIORAL MED CLINICAL TRIALS INFRASTRUCTURER24HL076857 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI SHEA, STEVEN A · 2004 to 2008
$3.5M
Practice-Based Trial of Blood Pressure Control in African AmericansR01HL087301 · NHLBI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI OGEDEGBE, OLUGBENGA G. · 2009 to 2010
$2.3M
Motivational Interviewing in Hypertensive African Ameri*R01HL069408 · NHLBI · WEILL MEDICAL COLLEGE OF CORNELL UNIV · PI OGEDEGBE, GBENGA GODWIN · 2001 to 2004
$1.4M
Explanatory Models of Hypertension in NigeriaR03TW007452 · FIC · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI OGEDEGBE, OLUGBENGA G. · 2006 to 2008
$100k
FIC NIH HHS R03 TW007452NHLBI NIH HHS R01 HL069408NHLBI NIH HHS R01 HL078566NHLBI NIH HHS R01 HL087301NHLBI NIH HHS R01 HL69408NHLBI NIH HHS R24 HL76857
6 · The paper itself

Abstract

backgroundPoor medication adherence is a significant problem in hypertensive African Americans. Although motivational interviewing (MINT) is effective for adoption and maintenance of health behaviors in patients with chronic diseases, its effect on medication adherence remains untested in this population.

methodsThis randomized controlled trial tested the effect of a practice-based MINT counseling vs. usual care (UC) on medication adherence and blood pressure (BP) in 190 hypertensive African Americans (88% women; mean age 54 years). Patients were recruited from two community-based primary care practices in New York City. The primary outcome was adherence measured by electronic pill monitors; the secondary outcome was within-patient change in office BP from baseline to 12 months.

resultsBaseline adherence was similar in both groups (56.2 and 56.6% for MINT and UC, respectively, P = 0.94). Based on intent-to-treat analysis using mixed-effects regression, a significant time x group interaction with model-predicted posttreatment adherence rates of 43 and 57% were found in the UC and MINT groups, respectively (P = 0.027), with a between-group difference of 14% (95% confidence interval, -0.2 to -27%). The between-group difference in systolic and diastolic BP was -6.1 mm Hg (P = 0.065) and -1.4 mm Hg (P = 0.465), respectively, in favor of the MINT group.

conclusionsA practice-based MINT counseling led to steady maintenance of medication adherence over time, compared to significant decline in adherence for UC patients. This effect was associated with a modest, nonsignificant trend toward a net reduction in systolic BP in favor of the MINT group.

Indexed as

Black or African AmericanAntihypertensive AgentsBlood PressureFemaleFollow-Up StudiesHumansHypertensionMaleMedication AdherenceMiddle AgedNew York CityTreatment OutcomeAntihypertensive Agents

Identifiers

PMID18654123
PMCPMC3747638
OpenAlexW2052176751

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.