ArticleJournal of neuroimmunology2008
Ingress of blood-borne macrophages across the blood-brain barrier in murine HIV-1 encephalitis.
Article in Journal of neuroimmunology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
9 citing papers in PubMed.
- Neuroprotectin D1 Protects Against Postoperative Delirium-Like Behavior in Aged Mice.Frontiers in aging neuroscience · 2020Article
- Bone marrow-derived macrophages from aged rats are more responsive to inflammatory stimuli.Journal of neuroinflammation · 2015Article
- Landmark optimization using local curvature for point-based nonlinear rodent brain image registration.International journal of biomedical imaging · 2012Article
- Macrophage endocytic trafficking of antiretroviral nanoparticles.Nanomedicine (London, England) · 2011Article
- Bio-inspired, bioengineered and biomimetic drug delivery carriers.Nature reviews. Drug discovery · 2011Review
- Neuroimmune pharmacology as a sub-discipline of medical neuroscience in the medical school curriculum.Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology · 2011Review
- Registered bioimaging of nanomaterials for diagnostic and therapeutic monitoring.Journal of visualized experiments : JoVE · 2010Article
- Macrophage delivery of nanoformulated antiretroviral drug to the brain in a murine model of neuroAIDS.Journal of immunology (Baltimore, Md. : 1950) · 2009Article
- NanoART, neuroAIDS and CNS drug delivery.Nanomedicine (London, England) · 2009Review
Corrections and comments
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Authors and funding
9 authors.
Funding
Abstract
Blood-borne macrophage ingress into brain in HIV-1 associated neurocognitive disorders governs the tempo of disease. We used superparamagnetic iron-oxide particles loaded into murine bone marrow-derived macrophages (BMM) injected intravenously into HIV-1 encephalitis mice to quantitatively assess BMM entry into diseased brain regions. Magnetic resonance imaging tests were validated by histological coregistration and enhanced image processing. The demonstration of robust BMM migration into areas of focal encephalitis provide 'proof of concept' for the use of MRI to monitor macrophage ingress into brain.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.