ArticleBrain pathology (Zurich, Switzerland)2009
Chordoid glioma: a case report and molecular characterization of five cases.
Article in Brain pathology (Zurich, Switzerland), 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
10 citing papers in PubMed, 2 syntheses or guidelines pooled it, 37 citations in OpenAlex.
- Surgical strategies and long-term survival for third ventricle chordoid gliomas: a systematic review and clinical algorithm.Neurosurgical review · 2026Pooled it
- Prognostic factors for recurrence and complications in the surgical management of primary chordoid gliomas: A systematic review of literature.Clinical neurology and neurosurgery · 2015Pooled it
- Major Features of the 2021 WHO Classification of CNS Tumors.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2022Review
- One of a kind-chordoid glioma in the fourth ventricle: a case report and literature review.Acta radiologica open · 2020Article
- A recurrent kinase domain mutation in PRKCA defines chordoid glioma of the third ventricle.Nature communications · 2018Article
- Chordoid glioma of the third ventricle: report of a rapidly progressive case.Journal of neuro-oncology · 2017Article
- Chordoid glioma of the third ventricle: a patient presenting with SIADH and a review of this rare tumor.Pituitary · 2016Review
- The prognostic value of Ki-67, p53, epidermal growth factor receptor, 1p36, 9p21, 10q23, and 17p13 in skull base chordomas.Archives of pathology & laboratory medicine · 2010Article
- Chordoid glioma : a case report of unusual location and neuroradiological characteristics.Journal of Korean Neurosurgical Society · 2010Article
- YKL-40 is directly produced by tumor cells and is inversely linked to EGFR in glioblastomas.International journal of clinical and experimental pathology · 2010Article
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Chordoid gliomas are rare, slow-growing neoplasms of the anterior third ventricle. We reported a case of chordoid glioma in a 41-year-old man with obstructive hydrocephalus. Histologically, the tumor consisted of polygonal epithelioid cells admixed with elongated cells in a myxoid stroma. A prominent lymphoplasmacytic infiltrate was present. The tumor cells expressed glial fibrillary acidic protein (GFAP), epithelial membrane antigen (EMA), vimentin, CD31, CD34, epidermal growth factor receptor (EGFR) and S100 but were negative for pankeratin and E-cadherin. The percentage of Ki67 positive cells was approximately 3%. Weak p53 immunoreactivity was seen in less than 10% of the cells. Array comparative genomic hybridization performed on this case, as well as on four other archived cases, showed losses at several loci. Fluorescence in situ hybridization (FISH) confirmed consistent genetic alterations at 9p21 and 11q13. These are the fifth through ninth reported cases of chordoid gliomas with molecular characterization suggesting a distinct genetic origin from other gliomas.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.