A paper, made visible
SLCO1B1 variants and statin-induced myopathy--a genomewide study.
- Available sources do not yet support a numeric visual.
What the available source describes
Study context is available. A quantitative result is not established here.
Study context 1 · source-backed descriptions
No supported numerical result is available for this comparison. No supported numeric visual is available.
What was examined
statin therapy
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- Paper abstract ↗ · Abstractabstract · Matched to source text; not expert scientific review
The odds ratio for myopathy was 4.5 (95% confidence interval [CI], 2.6 to 7.7) per copy of the C allele, and 16.9 (95% CI, 4.7 to 61.1) in CC as compared with TT homozygotes.
- Paper abstract ↗ · Abstractabstract · Matched to source text; not expert scientific review
BACKGROUND: Lowering low-density lipoprotein cholesterol with statin therapy results in substantial reductions in cardiovascular events, and larger reductions in cholesterol may produce larger benefits.
Study context 2 · source-backed descriptions
No supported numerical result is available for this comparison. No supported numeric visual is available.
Outcome named in the source
cholesterol-lowering effects of simvastatin
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- Paper abstract ↗ · Abstractabstract · Matched to source text; not expert scientific review
The association of rs4149056 with myopathy was replicated in the trial of 40 mg of simvastatin daily, which also showed an association between rs4149056 and the cholesterol-lowering effects of simvastatin.
Study context 3 · source-backed descriptions
The numerical result is withheld from this picture. The estimate and interval could not be bound to one explicit statistical expression in the source.
What was examined
TT homozygotes
Outcome named in the source
myopathy
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- Paper abstract ↗ · Abstractabstract · Matched to source text; not expert scientific review
The odds ratio for myopathy was 4.5 (95% confidence interval [CI], 2.6 to 7.7) per copy of the C allele, and 16.9 (95% CI, 4.7 to 61.1) in CC as compared with TT homozygotes.
Study context 4 · source-backed descriptions
The numerical result is withheld from this picture. The estimate and interval could not be bound to one explicit statistical expression in the source.
What was examined
C allele
Outcome named in the source
myopathy
Inspect the source trail for this comparison
- Paper abstract ↗ · Abstractabstract · Matched to source text; not expert scientific review
The odds ratio for myopathy was 4.5 (95% confidence interval [CI], 2.6 to 7.7) per copy of the C allele, and 16.9 (95% CI, 4.7 to 61.1) in CC as compared with TT homozygotes.