Evidence map›Paper›PMID 18650443›Full record

ReviewThe Journal of biological chemistry2008

Proteases: multifunctional enzymes in life and disease.

Carlos López-Otín, Judith S Bond

Abstract readReview
In one paragraph

Review in The Journal of biological chemistry, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 412 papers.

0numbers the graph read from it
0cells of the map it votes in
412citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

412 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Achieving protease substrate-specific inhibition by mAb dual functional selections.Protein science : a publication of the Protein Society · 2026
    Article
  10. Article
  11. Article
  12. Review
  13. Review
  14. Review
  15. Review
  16. Article
  17. Article
  18. Article
  19. Review
  20. Article

352 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Carlos López-OtínDepartamento de Bioquímica y Biología Molecular, Facultad de Medicina, Instituto Universitario de Oncología, Universidad de Oviedo, 33006 Oviedo, Spain.
Judith S Bond

Funding

MEPRINS-METALLOPROTEINSASES OF THE KIDNEY AND INTESTINER01DK019691 · NIDDK · VIRGINIA POLYTECHNIC INST AND ST UNIV · PI BOND, JUDITH S · 1986 to 2010
$3.1M
MEPRINS - METALLOPROTEINASES OF THE KIDNEY AND INTESTINER56DK019691 · NIDDK · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI BOND, JUDITH S · 2005 to 2005
$73k
INTRACELLULAR PROTEIN CATABOLISM IN DIABETES MELLITUSR37DK019691 · NIDDK · VIRGINIA POLYTECHNIC INST AND ST UNIV · PI BOND, JUDITH S · 1989 to 1996
–
NIDDK NIH HHS DK-19691
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Evolution, MolecularPeptide HydrolasesSubstrate SpecificityPeptide Hydrolases

Identifiers

PMID18650443
PMCPMC2576539

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.