ArticleClinical journal of the American Society of Nephrology : CJASN2008
Determinants of 24-hour urinary oxalate excretion.
Article in Clinical journal of the American Society of Nephrology : CJASN, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 73 papers, 2 of them syntheses that pooled it.
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Who cites it
73 citing papers in PubMed, 2 syntheses or guidelines pooled it, 169 citations in OpenAlex.
- Metabolic diagnosis and medical prevention of calcium nephrolithiasis and its systemic manifestations: a consensus statement.Journal of nephrology · 2016Guideline
- Metabolic syndrome and nephrolithiasis: a systematic review and meta-analysis of the scientific evidence.Journal of nephrology · 2014Pooled it
- Daily Intake of Lemna minor or Spinach as Vegetable Does Not Show Significant Difference on Health Parameters and Taste Preference.Plant foods for human nutrition (Dordrecht, Netherlands) · 2022Trial
- Oxalic acid and diacylglycerol 36:3 are cross-species markers of sleep debt.Proceedings of the National Academy of Sciences of the United States of America · 2015Trial
- Trial
- Oxalate nephropathy causing renal failure in small bowel Crohn's disease: a case report.Journal of medical case reports · 2025Article
- Roadblocks of Urinary EV Biomarkers: Moving Toward the Clinic.Journal of extracellular vesicles · 2025Review
- Article
- Determination of the kidney stone composition using infrared spectroscopy in Iran at a national referral center during 2019-2023.Asian journal of urology · 2025Article
- Oxalate Nephropathy and the Mechanism of Oxalate-Induced Kidney Injury.Kidney diseases (Basel, Switzerland) · 2023Review
- Article
- Vitamins as regulators of calcium-containing kidney stones - new perspectives on the role of the gut microbiome.Nature reviews. Urology · 2023Review
- Oxalate (dys)Metabolism: Person-to-Person Variability, Kidney and Cardiometabolic Toxicity.Genes · 2023Review
- Determinants on urinary excretion of oxalate and other key factors related to urolithiasis among patients with chronic kidney disease: a single center study.Urolithiasis · 2023Article
- Fluid intake recommendations in urolithiasis and general advice to patients without metabolic risk factors.World journal of urology · 2023Article
- Increased abundance of bacteria of the family Muribaculaceae achieved by fecal microbiome transplantation correlates with the inhibition of kidney calcium oxalate stone deposition in experimental rats.Frontiers in cellular and infection microbiology · 2023Article
- Role of insulin resistance and the gut microbiome on urine oxalate excretion in ob/ob mice.Physiological reports · 2022Article
- Calcium deficiency worldwide: prevalence of inadequate intakes and associated health outcomes.Annals of the New York Academy of Sciences · 2022Article
- The health effects of soy: A reference guide for health professionals.Frontiers in nutrition · 2022Review
- Chemical evidence for the tradeoff-in-the-nephron hypothesis to explain secondary hyperparathyroidism.PloS one · 2022Article
13 more citing papers are in PubMed but not listed here.
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
BACKGROUND AND
objectivesHigher levels of urinary oxalate substantially increase the risk of calcium oxalate kidney stones. However, the determinants of urinary oxalate excretion are unclear. The objective was to examine the impact of dietary factors, age, body size, diabetes, and urinary factors on 24-h urinary oxalate. DESIGN, SETTING, PARTICIPANTS, AND MEASUREMENTS: We conducted a cross-sectional study of 3348 stone forming and non-stone-forming participants in the Health Professionals Follow-up Study (men), the Nurses' Health Study (older women), and the Nurses' Health Study II (younger women).
resultsMedian urinary oxalate was 39 mg/d in men, 27 mg/d in older women, and 26 mg/d in younger women. Participants in the highest quartile of dietary oxalate excreted 1.7 mg/d more urinary oxalate than participants in the lowest quartile (P trend 0.001). The relation between dietary and urinary oxalate was similar in individuals with and without nephrolithiasis. Participants consuming 1000 mg/d or more of vitamin C excreted 6.8 mg/d more urinary oxalate than participants consuming <90 mg/d (P trend < 0.001). Body mass index, total fructose intake, and 24-h urinary potassium, magnesium, and phosphorus levels also were positively associated with urinary oxalate. Calcium intake and age were inversely associated with urinary oxalate. After adjustment for body size, participants with diabetes excreted 2.0 mg/d more urinary oxalate than those without diabetes (P < 0.01).
conclusionsThe impact of dietary oxalate on urinary oxalate appears to be small. Further investigation of factors influencing urinary oxalate may lead to new approaches to prevent calcium kidney stones.
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