ArticleMolecular biology reports2009
Mutational analysis of the -10 region from the Mycobacterium tuberculosis lipF promoter.
Article in Molecular biology reports, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed, 6 citations in OpenAlex.
- LipF increases rifampicin and streptomycin sensitivity in a Mycobacterium tuberculosis surrogate.BMC microbiology · 2020Article
- Induction of the acid inducible lipF promoter is reversibly inhibited in pH ranges of pH 4.2-4.0.BMC research notes · 2018Article
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Authors and funding
2 authors at 2 institutions in 1 country.
Funding
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Abstract
The promoter driving expression of the Mycobacterium tuberculosis gene lipF (Rv3487c) had previously been identified as being upregulated by acidic stress. Subsequently a 59 base pair (bp) acid inducible minimal promoter region was isolated in which a putative -10 region was identified. In this study we use mutational analysis to investigate the -10 region of the lipF promoter. Mutations within this region lead to a dramatic decrease of promoter activity, while a mutation outside of this region does not affect promoter activity.
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