Evidence map›Paper›PMID 18648922›Full record

ArticleVirus genes2008

Structural and phylogenetic relationship of ORF 31 from the Anticarsia gemmatalis MNPV to poly (ADP-ribose) polymerases (PARP).

Juliana Velasco de Castro Oliveira, Fernando Lucas de Melo, Camila Malta Romano, Atila Iamarino, Thais Sampaio Rizzi, Fernanda Peres Yeda, Charlotte Marianna Hársi, José Luiz Caldas Wolff, Paolo Marinho de Andrade Zanotto

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Article in Virus genes, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 9 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Juliana Velasco de Castro OliveiraDepartamento de Microbiologia, Laboratório de Evolução Molecular e Bioinformática, Instituto de Ciências Biomédicas, Universidade de São Paulo, São Paulo, SP, Brazil.
Fernando Lucas de Melo
Camila Malta Romano
Atila Iamarino
Thais Sampaio Rizzi
Fernanda Peres Yeda
Charlotte Marianna Hársi
José Luiz Caldas Wolff
Paolo Marinho de Andrade Zanotto
Universidade de São Paulo · BRUniversidade de Mogi das Cruzes · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

ORF 31 is a unique baculovirus gene in the genome of Anticarsia gemmatalis multiple nucleopolyhedrovirus isolate 2D (AgMNPV-2D). It encodes a putative polypeptide of 369 aa homologous to poly (ADP-ribose) polymerase (PARP) found in the genomes of several organisms. Moreover, we found a phylogenetic association with Group I PARP proteins and a 3D homology model of its conserved PARP C-terminal catalytic domain indicating that had almost an exact spatial superimposition of <1 A with other PARP available structures. The 5' end of ORF 31 mRNA was located at the first nucleotide of a CATT motif at position -27. Using real-time PCR we detected transcripts at 3 h post-infection (p.i.) increasing until 24 h p.i., which coincides with the onset of DNA replication, suggestive of a possible role in DNA metabolism.

Indexed as

Open Reading FramesPhylogenyAmino Acid SequenceAnimalsCell LineModels, MolecularMolecular Sequence DataNucleopolyhedrovirusesPoly(ADP-ribose) PolymerasesSequence AlignmentSpodopteraViral ProteinsPoly(ADP-ribose) PolymerasesViral Proteins

Identifiers

PMID18648922
OpenAlexW2041409522

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.