Trial reportLangenbeck's archives of surgery2008
Ligasure versus Ultracision in thyroid surgery: a prospective randomized study.
Trial report in Langenbeck's archives of surgery, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01812395 (Is Superior Laryngeal Nerve Really Safe During Thyroidectomy Using Ultrasonic Dissector.), which is not on this map. Cited by 33 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Is Superior Laryngeal Nerve Really Safe During Thyroidectomy Using Ultrasonic Dissector.
Who cites it
33 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- The role of LigaSure™ and Harmonic Scalpel in the preservation of recurrent laryngeal nerve during thyroidectomy.Annals of the Royal College of Surgeons of England · 2022Pooled it
- ENERgized vessel sealing systems versus CONventional hemostasis techniques in thyroid surgery--the ENERCON systematic review and network meta-analysis.Langenbeck's archives of surgery · 2013Pooled it
- Sutureless thyroidectomy with energy-based devices: Cerrahpasa experience.Updates in surgery · 2013Trial
- Vascular clips versus ligatures in thyroid surgery--results of a multicenter randomized controlled trial (CLIVIT Trial).Langenbeck's archives of surgery · 2012Trial
- Harmonic Focus™ versus "knot tying" during total thyroidectomy: a randomized trial.Updates in surgery · 2011Trial
- Harmonic focus in total thyroidectomy plus level III-IV and VI dissection: a prospective randomized study.World journal of surgical oncology · 2011Trial
- Thyroidectomy with LigaSure.Surgery today · 2011Trial
- Update on sutureless thyroidectomy.Il Giornale di chirurgiaTrial
- Efficacy of the LigaSure system vs UltraCision harmonic scalpel in laparoscopic appendectomy for the management of acute appendicitis.Wideochirurgia i inne techniki maloinwazyjne = Videosurgery and other miniinvasive techniques · 2026Article
- Comparative analysis between ultrasonic shears versus advanced bipolar device in transoral endoscopic thyroidectomy: a randomized controlled trial.Gland surgery · 2023Article
- Single-port transaxillary robotic thyroidectomy (START): 200-cases with two-step retraction method.Surgical endoscopy · 2022Article
- Parathyroid hormone level after total thyroidectomy using conventional versus harmonic focus technique: Prospective randomized study.Annals of medicine and surgery (2012) · 2022Article
- Comparing LigasureGland surgery · 2020Article
- Association of Vessel-Sealant Devices vs Conventional Hemostasis With Postoperative Neck Hematoma After Thyroid Operations.JAMA surgery · 2019Observational
- Laparoscopic ultrasonic dissectors: technology update by a review of literature.Medical devices (Auckland, N.Z.) · 2019Review
- Bipolar Vessel Sealing System Versus Suture Ligation in Selective Neck Dissection.Journal of maxillofacial and oral surgery · 2018Article
- A comparison of surgical outcomes and complications between hemostatic devices for thyroid surgery: a network meta-analysis.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2017Review
- Parathyroid Autotransplantation During Thyroid Surgery: A Novel Technique Using a Cell Culture Nutrient Solution.World journal of surgery · 2017Article
- Harmonic versus LigaSure hemostasis technique in thyroid surgery: A meta-analysis.Biomedical reports · 2016Article
- Parathyroid function following total thyroidectomy using energy devices.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2016Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeNew hemostatic technologies (NT) are often employed in thyroid surgery in the effort to reduce operating time and complications. The aim of this study is to compare three different hemostatic techniques.
methodsThis is a prospective randomized study. There were 150 patients, aged 56 +/- 14 years, randomized for total thyroidectomy with conventional technique (CT), Ligasure vessel sealing system (LI) or Harmonic Scalpel (HS) at the university surgical department. One hundred thirty-five patients had benign diseases; 15 had malignancies.
resultsMean postoperative hospital stay was 2.6 days. Mean operation time was 113 +/- 31 min; in HS patients, it was significantly shorter (p < 0.001). Morbidity was 43.3%; mortality was nil. Morbidity was significantly different between CT and NT groups (p = 0.0002); HS and LI groups had a higher morbidity (p = 0.0001 and p = 0.02, respectively). Mean postoperative calcemia was 1.12 +/- 0.1 mmol/l with a significant difference between groups; NT patients had a significantly lower calcemia (p < 0.05). There was no difference in recurrent laryngeal nerve palsies and in intraoperative blood losses (p = ns).
conclusionsAccording to our experience, the only real advantage of new hemostatic technologies was a shorter operation time with HS.
Indexed as
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18648850What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.