Evidence map›Paper›PMID 18648746›Full record

ArticleJournal of gastroenterology2008

Primary CD56+ NK/T-cell lymphoma of the rectum accompanied with refractory ulcerative colitis.

Kazuki Kakimoto, Takuya Inoue, Takashi Nishikawa, Kumi Ishida, Ken Kawakami, Takanori Kuramoto, Yosuke Abe, Eijiro Morita, Naoko Murano, Ken Toshina and 8 more

Abstract readCase Reports
PubMed Publisher
In one paragraph

Article in Journal of gastroenterology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.4field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 2 institutions in 1 country.

Kazuki KakimotoSecond Department of Internal Medicine, Osaka Medical College, 2-7 Daigakumachi, Takatsuki 569-8686, Japan.
Takuya Inoue
Takashi Nishikawa
Kumi Ishida
Ken Kawakami
Takanori Kuramoto
Yosuke Abe
Eijiro Morita
Naoko Murano
Ken Toshina
Mitsuyuki Murano
Eiji Umegaki
Yutaro Egashira
Junji Okuda
Nobuhiko Tanigawa
Ichiro Hirata
Ken-Ichi Katsu
Kazuhide Higuchi
Osaka Medical and Pharmaceutical University · JPFujita Health University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A case of primary NK/T-cell lymphoma of the rectum accompanied with ulcerative colitis (UC) in a 73-year-old man is reported. He had a 6-year history of repeated admission to our hospital for UC. Total colonoscopy performed 4 months after resolution of refractory UC complicated by cytomegalovirus colitis showed a markedly submucosal tumor in the rectum, which was histologically diagnosed as malignant lymphoma. The findings of computed tomography of the chest and abdomen, gallium scintigraphy, abdominal ultrasonography, and upper gastrointestinal endoscopy showed no abnormal lesions. Therefore, based on a diagnosis of localized rectal lymphoma with UC, proctocolectomy was performed. The resected specimen showed three submucosal tumors in the rectum with local nodal involvement. Histologically, the tumors were characterized by diffusely infiltrating sheets of large atypical lymphoid cells, which were negative for CD4, CD8, and CD20 but were positive for CD56, CD3, and granzyme B. The presence of Epstein-Barr virus (EBV) infection in neoplastic cells was shown by in situ hybridization for EBV-encoded early small RNA1 (EBER-1). Based on these findings, the patient was diagnosed with primary CD56+ NK/T-cell lymphoma of the rectum (stage IIE). This is the first case report of primary rectal NK/T-cell lymphoma accompanied with UC.

Indexed as

AgedCD56 AntigenColitis, UlcerativeHumansImmunohistochemistryLymphoma, Extranodal NK-T-CellMaleRectal NeoplasmsCD56 Antigen

Identifiers

PMID18648746
OpenAlexW2139069187

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.