ArticleDose-response : a publication of International Hormesis Society2006
In vivo mutagenic effect of very low dose radiation.
Article in Dose-response : a publication of International Hormesis Society, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
10 citing papers in PubMed, 27 citations in OpenAlex.
- Low Radiation Environment Switches the Overgrowth-Induced Cell Apoptosis Toward Autophagy.Frontiers in public health · 2020Article
- Low-dose or low-dose-rate ionizing radiation-induced bioeffects in animal models.Journal of radiation research · 2017Review
- Global gene expression responses to low- or high-dose radiation in a human three-dimensional tissue model.Radiation research · 2011Article
- Radiation exposure from imaging tests: is there an increased cancer risk?Expert review of cardiovascular therapy · 2011Review
- Assessing cancer risks of low-dose radiation.Nature reviews. Cancer · 2009Review
- Non-problematic risks from low-dose radiation-induced DNA damage clusters.Dose-response : a publication of International Hormesis Society · 2008Article
- It's time for a new low-dose-radiation risk assessment paradigm--one that acknowledges hormesis.Dose-response : a publication of International Hormesis Society · 2008Article
- It Is Time to Move Beyond the Linear No-Threshold Theory for Low-Dose Radiation Protection.Dose-response : a publication of International Hormesis SocietyArticle
- The Lowest Radiation Dose Having Molecular Changes in the Living Body.Dose-response : a publication of International Hormesis SocietyArticle
- Triphasic Dose-Response of Hematological Parameters in Healthcare Workers Exposed to Ionizing Radiations.Dose-response : a publication of International Hormesis SocietyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Almost all of our knowledge about the mutational effect of radiation has come from high dose studies which are generally not relevant to public exposure. The pKZ1 mouse recombination mutagenesis assay enables study of the mutational effect of very low doses of low LET radiation (microGy to cGy range) in a whole animal model. The mutational end-point studied is chromosomal inversion which is a common mutation in cancer. We have observed 1) a non-linear dose response of induced inversions in pKZ1 mice exposed to a wide dose range of low LET radiation, 2) the ability of low priming doses to cause an adaptive response to subsequent higher test doses and 3) the effect of genetic susceptibility where animals that are heterozygous for the Ataxia Telangiectasia gene (Atm) exhibit different responses to low dose radiation compared to their normal litter-mates.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.