Evidence map›Paper›PMID 18647860›Full record

ArticleSexually transmitted infections2008

Bayesian melding for estimating uncertainty in national HIV prevalence estimates.

L Alkema, A E Raftery, T Brown

Abstract readMulticenter Study
In one paragraph

Article in Sexually transmitted infections, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

L AlkemaUniversity of Washington, Center for Statistics and the Social Sciences, Seattle, Washington, USA. alkema@u.washington.edu
A E Raftery
T Brown

Funding

Methods and Data CoreR24HD042828 · NICHD · UNIVERSITY OF WASHINGTON · PI TOLNAY, STEWART E · 2002 to 2016
$9.3M
Sexually Transmitted Infection Epidemics: Bayesian Prevalence & Size EstimateR01HD054511 · NICHD · UNIVERSITY OF WASHINGTON · PI RAFTERY, ADRIAN E · 2007 to 2016
$3.2M
Population Research TrainingT32HD007543 · NICHD · UNIVERSITY OF WASHINGTON · PI CURRAN, SARA R. · 2002 to 2016
$2.3M
NICHD NIH HHS R01 HD054511NICHD NIH HHS R24 HD042828NICHD NIH HHS T32 HD007543
6 · The paper itself

Abstract

objectiveTo construct confidence intervals for HIV prevalence in countries with generalised epidemics.

methodsIn the Bayesian melding approach, a sample of country-specific epidemic curves describing HIV prevalence over time is derived based on time series of antenatal clinic prevalence data and general information on the parameters that describe the HIV epidemic. The prevalence trends at antenatal clinics are calibrated to population-based HIV prevalence estimates from national surveys. For countries without population based estimates, a general calibration method is developed. Based on the sample of calibrated epidemic curves, we derive annual 95% confidence intervals for HIV prevalence. The curve that best represents the data at antenatal clinics and population-based surveys, as well as general information about the epidemic, is chosen to represent the best estimates and predictions.

resultsWe present results for urban areas in Haiti and Namibia to illustrate the estimates and confidence intervals that are derived with the methodology.

Indexed as

AdolescentAdultBayes TheoremConfidence IntervalsData CollectionDisease OutbreaksFemaleHaitiHIV InfectionsHumansMaleMiddle AgedNamibiaPrevalenceUncertaintyUnited Nations

Identifiers

PMID18647860
PMCPMC2569139

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LicenceCC BY
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.