ArticleProceedings of the National Academy of Sciences of the United States of America2008
UV excitation of single DNA and RNA strands produces high yields of exciplex states between two stacked bases.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
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Who cites it
28 citing papers in PubMed.
- Setting the Bases of the Photogenotoxicity ofJournal of chemical information and modeling · 2026Article
- Spectroscopic Super-resolution Imaging of DNA Molecules using Intrinsic Contrast.Journal of visualized experiments : JoVE · 2026Article
- Effects of environmental noise on quantum charge diffusion in DNA sequences.Scientific reports · 2025Article
- Effect of Alkyl- vs Alkoxy-Arene Substituents on the Deactivation Processes and Fluorescence Quantum Yields of Exciplexes.The journal of physical chemistry. A · 2024Article
- Factors Affecting the Population of Excited Charge Transfer States in Adenine/Guanine Dinucleotides: A Joint Computational and Transient Absorption Study.Biomolecules · 2024Article
- Real-time observation of sub-100-fs charge and energy transfer processes in DNA dinucleotides.Chemical science · 2024Article
- The photoactivated dynamics of dGpdC and dCpdG sequences in DNA: a comprehensive quantum mechanical study.Chemical science · 2024Article
- Mechanisms of Nanoscale Radiation Enhancement by Metal Nanoparticles: Role of Low Energy Electrons.International journal of molecular sciences · 2023Review
- Nucleotide-amino acid π-stacking interactions initiate photo cross-linking in RNA-protein complexes.Nature communications · 2022Article
- Exciton decay mechanism in DNA single strands: back-electron transfer and ultrafast base motions.Chemical science · 2022Article
- Linear and nonlinear optical properties of transfer ribonucleic acid (tRNA) thin solid films.RSC advances · 2022Article
- The epigenetic DNA modification 5-carboxylcytosine promotes high levels of cyclobutane pyrimidine dimer formation upon UVB irradiation.Genome instability & disease · 2021Article
- What Makes Thienoguanosine an Outstanding Fluorescent DNA Probe?Journal of the American Chemical Society · 2020Article
- Excimer Intermediates en Route to Long-Lived Charge-Transfer States in Single-Stranded Adenine DNA as Revealed by Nonadiabatic Dynamics.The journal of physical chemistry letters · 2020Article
- UV-Induced Charge-Transfer States in Short Guanosine-Containing DNA Oligonucleotides.Chembiochem : a European journal of chemical biology · 2020Article
- Electron-driven proton transfer relieves excited-state antiaromaticity in photoexcited DNA base pairs.Chemical science · 2020Article
- White light emission produced by CTMA-DNA nanolayers embedded with a mixture of organic light-emitting molecules.RSC advances · 2019Article
- Electronic delocalization, charge transfer and hypochromism in the UV absorption spectrum of polyadenine unravelled by multiscale computations and quantitative wavefunction analysis.Chemical science · 2017Article
- Stochastic fluorescence switching of nucleic acids under visible light illumination.Optics express · 2017Article
- Multiple Decay Mechanisms and 2D-UV Spectroscopic Fingerprints of Singlet Excited Solvated Adenine-Uracil Monophosphate.Chemistry (Weinheim an der Bergstrasse, Germany) · 2016Article
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5 authors.
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Abstract
Excited electronic states created by UV excitation of the diribonucleoside monophosphates ApA, ApG, ApC, ApU, and CpG were studied by the femtosecond transient-absorption technique. Bleach recovery signals recorded at 252 nm show that long-lived excited states are formed in all five dinucleosides. The lifetimes of these states exceed those measured in equimolar mixtures of the constituent mononucleotides by one to two orders of magnitude, indicating that electronic coupling between proximal nucleobases dramatically slows the relaxation of excess electronic energy. The decay rates of the long-lived states decrease with increasing energy of the charge-transfer state produced by transferring an electron from one base to another. The charge-transfer character of the long-lived states revealed by this analysis supports their assignment to excimer or exciplex states. Identical bleach recovery signals were seen for ApA, (A)(4), and poly(A) at delay times >10 ps after photoexcitation. This indicates that excited states localized on a stack of just two bases are the common trap states independent of the number of stacked nucleotides. The fraction of initial excitations that decay to long-lived exciplex states is approximately equal to the fraction of stacked bases determined by NMR measurements. This supports a model in which excitations associated with two stacked bases decay to exciplex states, whereas excitations in unstacked bases decay via ultrafast internal conversion. These results establish the importance of charge transfer-quenching pathways for UV-irradiated RNA and DNA in room-temperature solution.
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