Evidence map›Paper›PMID 18646155›Full record

SynthesisThe Cochrane database of systematic reviews2008

Open surgical procedures for incisional hernias.

Dennis den Hartog, Alphons H M Dur, Wim E Tuinebreijer, Robert W Kreis

Open access · greenAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in The Cochrane database of systematic reviews, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 137 papers, 16 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
137citing papers in PubMed, 16 pooled it
17.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

137 citing papers in PubMed, 16 syntheses or guidelines pooled it, 328 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Mesh fixation techniques in primary ventral or incisional hernia repair.The Cochrane database of systematic reviews · 2021
    Pooled it
  4. Ventral hernia recurrence in women of childbearing age: a systematic review and meta-analysis.Hernia : the journal of hernias and abdominal wall surgery · 2018
    Pooled it
  5. The use of adjuncts to reduce seroma in open incisional hernia repair: a systematic review.Hernia : the journal of hernias and abdominal wall surgery · 2018
    Pooled it
  6. Pooled it
  7. Pooled it
  8. Pooled it
  9. Pooled it
  10. Abdominal wall hernia and pregnancy: a systematic review.Hernia : the journal of hernias and abdominal wall surgery · 2015
    Pooled it
  11. A systematic review of the surgical treatment of large incisional hernia.Hernia : the journal of hernias and abdominal wall surgery · 2015
    Pooled it
  12. Surgical treatment for giant incisional hernia: a qualitative systematic review.Hernia : the journal of hernias and abdominal wall surgery · 2014
    Pooled it
  13. Pooled it
  14. Pooled it
  15. Pooled it
  16. Open surgical procedures for incisional hernias.The Cochrane database of systematic reviews · 2008
    Pooled it
  17. Trial
  18. Trial
  19. Trial
  20. Trial

77 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Dennis den HartogSurgery, Erasmus MC, University Medical Center Rotterdam, P.O. Box 2040, 's Gravendijkwal 230, Rotterdam, Netherlands, 3000 CA.
Alphons H M Dur
Wim E Tuinebreijer
Robert W Kreis
Association of Dutch Burn Centres · NLErasmus MC · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIncisional hernias occur frequently after abdominal surgery and can cause serious complications. The choice of a type of open operative repair is controversial. Determining the type of open operative repair is controversial, as the recurrence rate may be as high as 54%.

objectivesTo identify the best available open operative techniques for incisional hernias. SEARCH STRATEGY: Electronic databases MEDLINE, EMBASE, LILACS, and the Cochrane Central Register of Controlled Trials (CENTRAL) were searched from 1990 to 2007 and trials were identified from the known trial reference lists. SELECTION CRITERIA: Studies were eligible for inclusion if they were randomized trials comparing different techniques for open operative techniques for incisional hernias. DATA COLLECTION AND ANALYSIS: Statistical analyses were performed using the fixed effects model. Results were expressed as relative risk for dichotomous outcomes and weighted mean difference for continuous outcomes with 95% confidence intervals. MAIN

resultsEight trials comparing different open repairs for incisional hernias were identified; one trial was excluded. The included studies enrolled 1,141 patients. The results of three trials comparing suture repair versus mesh repair were pooled. Hernia recurrence was more frequent, wound infection less frequent in the direct suture group compared to the onlay or sublay mesh groups. The recurrence rates of two trials comparing onlay and sublay positions were pooled. This comparison yielded no difference in recurrences (two studies pooled), although operation time was shorter in the onlay group (one study). No difference was found in recurrence, satisfaction with cosmetics, or infection between the onlay standard mesh and skin autograft groups, following analysis pooling the two treatment arms. However, the analysis demonstrated less pain in the skin autograft group. Other trials comparing different mesh materials or different positions of the mesh, or comparing mesh with the components separation technique are described individually. The comparison between lightweight and standard mesh showed a trend for more recurrences in the lightweight group. The comparison between onlay and intraperitoneal mesh positions resulted in non significant fewer hernia recurrences, less seroma formation and more postoperative pain in the intraperitoneal group. No differences in the recurrence rates between the components separation and the intraperitoneal mesh technique. AUTHORS'

conclusionsThere is good evidence from three trials that open mesh repair is superior to suture repair in terms of recurrences, but inferior when considering wound infection. Six trials yielded insufficient evidence as to which type of mesh or which mesh position (on- or sublay) should be used. There was also insufficient evidence to advocate the use of the components separation technique.

Indexed as

Surgical MeshAbdominal WallHernia, VentralHumansPostoperative ComplicationsRandomized Controlled Trials as TopicRecurrenceSuture Techniques

Identifiers

PMID18646155
PMCPMC8924951
OpenAlexW1859928327

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.