Evidence map›Paper›PMID 18642122›Full record

ArticleSocial psychiatry and psychiatric epidemiology2009

The role of comorbidity in the detection of psychiatric disorders with checklists for mental and physical symptoms in primary care.

Margot W M de Waal, Ingrid A Arnold, Philip Spinhoven, Just A H Eekhof, Willem J J Assendelft, Albert M van Hemert

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In one paragraph

Article in Social psychiatry and psychiatric epidemiology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Margot W M de WaalDepartment of Public Health and Primary Care, Leiden University Medical Center, 2300 RC, Leiden, The Netherlands. m.w.m.de_waal@lumc.nl
Ingrid A Arnold
Philip Spinhoven
Just A H Eekhof
Willem J J Assendelft
Albert M van Hemert

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo examine the contribution of a mental and physical symptom count to the detection of single or comorbid anxiety, depressive and somatoform disorders.

methodIn primary care 1,046 consulting patients completed the Hospital Anxiety and Depression Scale (HADS) and the Physical Symptom Checklist (PSC-51). In a stratified sample of 473 patients DSM-IV psychiatric disorders were assessed using the WHO-SCAN interview. The diagnostic value of the HADS total score and the PSC-51 symptom count was examined with ROC-analyses.

resultsThe discriminative power of PSC-51 and HADS was highest for patients with both a somatoform disorder and an anxiety or depressive disorder, with an AUC of 0.86 (95% CI: 0.81-0.91) and 0.91 (95% CI: 0.87-0.94) respectively. Using both symptom counts together did not increase the diagnostic value for the detection of the psychiatric disorders.

conclusionBoth symptom counts preferentially detected patients with comorbid disorders. When interpreting diagnostic values of screening questionnaires one should keep in mind that the validity of these values can be dependent of the presence of comorbid disorders.

Indexed as

AdultAffective SymptomsAgedAged, 80 and overAge DistributionComorbidityDepressionFemaleHumansMaleMental DisordersMiddle AgedNetherlandsPrimary Health CarePsychiatric Status Rating ScalesROC Curve

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.