ArticleSocial psychiatry and psychiatric epidemiology2009
Outcome study of first-episode schizophrenia in a developing country: quality of life and antipsychotics.
Article in Social psychiatry and psychiatric epidemiology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
5 citing papers in PubMed, 16 citations in OpenAlex.
- Quality of life and its predictors in first-episode schizophrenia and individuals at clinical high-risk for psychosis.BMC psychiatry · 2023Article
- Master's level mental health nursing competencies, a prerequisite for equal health among service users in mental health care.International journal of qualitative studies on health and well-being · 2018Article
- Clients' experiences of the Boston Psychiatric Rehabilitation Approach: a qualitative study.International journal of qualitative studies on health and well-being · 2014Article
- Factors affecting treatment discontinuation and treatment outcome in patients with schizophrenia in Korea: 10-year follow-up study.Psychiatry investigation · 2011Article
- Attitudes towards health among patients and staff in mental health services: a comparison of ratings of importance of different items of health.Social psychiatry and psychiatric epidemiology · 2010Article
Corrections and comments
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Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimQuality of life has recently been emphasized in the management of schizophrenia, yet data from developing country is lacking. We explored the differences in subjective quality of life between conventional antipsychotics (CAs) and atypical antipsychotics (AAs).
methodsThis is a naturalistic study conducted in Kuala Lumpur, Malaysia. Patients with first-episode schizophrenia and related psychosis were recruited from Kuala Lumpur Hospital. WHOQOL-BREF, side effects of medications and other variables were assessed after 1 year of treatment in routine clinical situation.
resultsThe study comprised 120 adults. There were no significant statistical differences between groups concerning subjective quality of life, extrapyramidal side effects and employment. Significant less benzhexol usage was reported among AAs (P<0.001) compared to CAs and sulpiride.
conclusionPatients treated with CAs, sulpiride or AAs experienced similar quality of life, clinical and health outcomes after 1 year commencing treatment. Overall, the results are in line with other major pragmatic clinical trials. This study also found sulpiride cost-effective.
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