Evidence map›Paper›PMID 18641423›Full record

ArticleThe Canadian journal of clinical pharmacology = Journal canadien de pharmacologie clinique2008

Does knowledge of medication prices predict physicians' support for cost effective prescribing policies.

Jennifer M Polinski, Malcolm Maclure, Blair Marshall, Alan Cassels, Jessica Agnew-Blais, Amanda R Patrick, Sebastian Schneeweiss

Open access · greenAbstract read
In one paragraph

Article in The Canadian journal of clinical pharmacology = Journal canadien de pharmacologie clinique, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
4.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

  1. Pooled it
  2. Understanding US Physician and Pharmacist Attitudes Toward Biosimilar Products: A Qualitative Study.BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy · 2022
    Article
  3. Article
  4. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Jennifer M PolinskiDivision of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women's Hospital, Boston, MA, USA. jpolinski@partners.org
Malcolm Maclure
Blair Marshall
Alan Cassels
Jessica Agnew-Blais
Amanda R Patrick
Sebastian Schneeweiss
Brigham and Women's Hospital · US

Funding

Effects of income-based drug charges on older PatientsR01AG021950 · NIA · BRIGHAM AND WOMEN'S HOSPITAL · PI SCHNEEWEISS, SEBASTIAN G. · 2003 to 2006
$1.3M
CONSEQUENCES OF DRUG COST SHARING IN THE ELDERLYR01HS010881 · AHRQ · BRIGHAM AND WOMEN'S HOSPITAL · PI SCHNEEWEISS, SEBASTIAN G. · 2000 to 2006
$263k
AHRQ HHS R01 HS010881NIA NIH HHS R01 AG021950
6 · The paper itself

Abstract

backgroundBritish Columbia implemented a generic substitution (GS) and Reference Drug Program (RDP) to contain drug expenditures without negatively affecting health outcomes. Years after implementation, these policies remain controversial among physicians.

objectiveTo assess British Columbia general practitioners' (GPs) opinions of RDP and GS stratified by knowledge of drug costs.

methodsIn telephone interviews, GPs ranked the economic and clinical appropriateness of drug policy options on a 5-point Likert scale. Responses to economic questions were stratified and compared according to the accuracy (+ $10 of the actual cost) of GPs' cost estimates for a 30-day supply of atorvastatin and omeprazole.

resultsThe majority of 210 interviewed GPs rated the economic appropriateness of GS and RDP positively (79% and 65%) but fewer rated them clinically appropriate (60% and 43%). Ratings for GS were more favorable than RDP, economically (mean=4.3 vs. 3.8, p=0.0005) and clinically (mean=3.7 vs. 3.1, p=0.006). GP's assessment of the therapeutic equivalence among ACE inhibitors and among CCBs correlated with their ratings of the respective RDPs (I=0.3, p=0.03, and I=0.4, p=0.02). GPs underestimated the price for omeprazole by C$28 (33%) and atorvastatin by C$28 (34%). GPs with accurate cost estimates were equally as likely to favorably rank the economic appropriateness of RDP as those with inaccurate estimates (mean = 3.7 vs. 4.0, p=0.0847). GS was assessed similarly (mean = 4.2 vs. 4.5, p=0.0712).

conclusionsIn British Columbia, the majority of GPs hold favorable opinions of GS and RDP; but, simply educating physicians about drug prices will not make them more supportive of cost-containment policies.

Indexed as

Drug CostsHealth Knowledge, Attitudes, PracticePractice Patterns, Physicians'Prescription FeesAtorvastatinBritish ColumbiaCost-Benefit AnalysisCost ControlDrug PrescriptionsDrugs, GenericFamily PracticeHeptanoic AcidsHumansPyrrolesAtorvastatinDrugs, GenericHeptanoic AcidsPyrroles

Identifiers

PMID18641423
PMCPMC2913604
OpenAlexW1506550295

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.