ReviewPhilosophical transactions of the Royal Society of London. Series B, Biological sciences2008
Review. Neurogenetic studies of alcohol addiction.
Review in Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
39 citing papers in PubMed.
- Article
- Translational opportunities in animal and human models to study alcohol use disorder.Translational psychiatry · 2021Review
- Flying Together:International journal of molecular sciences · 2020Review
- Identification ofeLife · 2020Article
- Exploratory locomotion, a predictor of addiction vulnerability, is oligogenic in rats selected for this phenotype.Proceedings of the National Academy of Sciences of the United States of America · 2019Article
- A Genetic Animal Model of Alcoholism for Screening Medications to Treat Addiction.International review of neurobiology · 2016Review
- Amphetamine self-administration and dopamine function: assessment of gene × environment interactions in Lewis and Fischer 344 rats.Psychopharmacology · 2015Article
- Genetic relationship between ethanol-induced conditioned place preference and other ethanol phenotypes in 15 inbred mouse strains.Behavioral neuroscience · 2014Article
- Animal models of excessive alcohol consumption: recent advances and future challenges.Alcohol (Fayetteville, N.Y.) · 2014Article
- Scheduled access alcohol drinking by alcohol-preferring (P) and high-alcohol-drinking (HAD) rats: modeling adolescent and adult binge-like drinking.Alcohol (Fayetteville, N.Y.) · 2014Review
- Determining the heritability of ethanol-induced locomotor sensitization in mice using short-term behavioral selection.Psychopharmacology · 2013Article
- Escalation of intake under intermittent ethanol access in diverse mouse genotypes.Addiction biology · 2013Article
- Pharmacological characterization of the 20% alcohol intermittent access model in Sardinian alcohol-preferring rats: a model of binge-like drinking.Alcoholism, clinical and experimental research · 2013Article
- Epigenetic control of gene expression in the alcoholic brain.Alcohol research : current reviews · 2013Review
- Modeling the diagnostic criteria for alcohol dependence with genetic animal models.Current topics in behavioral neurosciences · 2013Review
- Evidence for multiple genetic factors underlying the DSM-IV criteria for alcohol dependence.Molecular psychiatry · 2012Article
- Animal models for medications development targeting alcohol abuse using selectively bred rat lines: neurobiological and pharmacological validity.Pharmacology, biochemistry, and behavior · 2012Review
- Gene Expression Under the Influence: Transcriptional Profiling of Ethanol in the Brain.Current psychopharmacology · 2012Article
- Ethanol sensitivity in high drinking in the dark selectively bred mice.Alcoholism, clinical and experimental research · 2012Article
- Oral Nicotine Self-Administration in Rodents.Journal of addiction research & therapy · 2012Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
Abstract
Neurogenetic studies of alcohol dependence have relied substantially on genetic animal models, particularly rodents. Studies of inbred strains, selectively bred lines and mutants bearing genes whose function has been targeted for over or under expression are reviewed. Studies focused on gene expression changes are the most recent contributors to this literature, and some genetic effects may work through epigenetic mechanisms. In a few instances, interesting parallels have been revealed between genetic risk in humans and studies in non-human animal models. Future approaches are likely to be increasingly complex.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.